Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50028802
TargetNeuropeptide Y receptor type 5(Rat)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268532BDBM50268532(3-oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[isobenzo...)
Affinity DataIC50: 0.670nMAssay Description:Displacement of [125I]PYY from rat NPY Y5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268739BDBM50268739(N-(3-(4-chlorophenyl)isoxazol-5-yl)-3-oxo-3H-spiro...)
Affinity DataIC50: 0.690nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268737BDBM50268737(N-(3-(2-chlorophenyl)isoxazol-5-yl)-3-oxo-3H-spiro...)
Affinity DataIC50: 0.830nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268700BDBM50268700(3-oxo-N-(3-phenylisoxazol-5-yl)-3H-spiro[isobenzof...)
Affinity DataIC50: 0.840nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268651BDBM50268651(3-oxo-N-(5-(3-(trifluoromethyl)phenyl)pyrimidin-2-...)
Affinity DataIC50: 0.850nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268534BDBM50268534(N-(5-(3-chlorophenyl)pyrimidin-2-yl)-3-oxo-3H-spir...)
Affinity DataIC50: 0.910nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268597BDBM50268597(N-(5-(2-fluorophenyl)pyrimidin-2-yl)-3-oxo-3H-spir...)
Affinity DataIC50: 0.990nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268738BDBM50268738(N-(3-(3-chlorophenyl)isoxazol-5-yl)-3-oxo-3H-spiro...)
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268594BDBM50268594(N-(5-(2-methoxyphenyl)pyrimidin-2-yl)-3-oxo-3H-spi...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268533BDBM50268533(N-(5-(2-chlorophenyl)pyrimidin-2-yl)-3-oxo-3H-spir...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268648BDBM50268648(N-(5-(3-fluorophenyl)pyrimidin-2-yl)-3-oxo-3H-spir...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268883BDBM50268883(3-oxo-N-(5-phenyl-1,2,4-thiadiazol-3-yl)-3H-spiro[...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Rat)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268739BDBM50268739(N-(3-(4-chlorophenyl)isoxazol-5-yl)-3-oxo-3H-spiro...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]PYY from rat NPY Y5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268650BDBM50268650(3-oxo-N-(5-(2-(trifluoromethyl)phenyl)pyrimidin-2-...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268532BDBM50268532(3-oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[isobenzo...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Mouse)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249869BDBM50249869(3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Rat)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249869BDBM50249869(3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]PYY from rat NPY Y5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268467BDBM50268467(3-oxo-N-(5-phenylpyrazin-2-yl)-3,4-dihydro-2H-spir...)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268595BDBM50268595(N-(5-(3-methoxyphenyl)pyrimidin-2-yl)-3-oxo-3H-spi...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268777BDBM50268777(3-oxo-N-(5-phenylthiazol-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268740BDBM50268740(3-oxo-N-(3-phenyl-1H-pyrazol-5-yl)-3H-spiro[isoben...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268698BDBM50268698(3-oxo-N-(2-phenylpyrimidin-5-yl)-3H-spiro[isobenzo...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268775BDBM50268775(3-oxo-N-(1-phenyl-1H-pyrazol-4-yl)-3H-spiro[isoben...)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268649BDBM50268649(N-(5-(4-fluorophenyl)pyrimidin-2-yl)-3-oxo-3H-spir...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249869BDBM50249869(3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268774BDBM50268774(3-oxo-N-(1-phenyl-1H-pyrazol-3-yl)-3H-spiro[isoben...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268884BDBM50268884(3-oxo-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-3H-spiro[...)
Affinity DataIC50: 3.40nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268776BDBM50268776(3-oxo-N-(1-phenyl-1H-imidazol-4-yl)-3H-spiro[isobe...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268306BDBM50268306(3-oxo-N-(5-phenylpyrazin-2-yl)spiro[isoindoline-1,...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268535BDBM50268535(N-(5-(4-chlorophenyl)pyrimidin-2-yl)-3-oxo-3H-spir...)
Affinity DataIC50: 3.90nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268469BDBM50268469(3-oxo-N-(5-phenylpyrazin-2-yl)spiro[isochroman-1,4...)
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249869BDBM50249869(3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity at human recombinant NPY Y5 receptor expressed in mouse LMtk- cells assessed as inhibition of NPY-induced Ca2+ increaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268699BDBM50268699(3-oxo-N-(6-phenylpyridazin-3-yl)-3H-spiro[isobenzo...)
Affinity DataIC50: 6.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268778BDBM50268778(3-oxo-N-(4-phenylthiazol-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50: 7.90nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268596BDBM50268596(N-(5-(4-methoxyphenyl)pyrimidin-2-yl)-3-oxo-3H-spi...)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268697BDBM50268697(3-oxo-N-(5-(4-(trifluoromethyl)phenyl)pyrimidin-2-...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268358BDBM50268358(N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofuran-1,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268305BDBM50268305(2-methyl-3-oxo-N-(5-phenylpyrazin-2-yl)spiro[isoin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268470BDBM50268470(N-(5-phenylpyrazin-2-yl)spiro[isochroman-1,4'-pipe...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268468BDBM50268468(1-oxo-N-(5-phenylpyrazin-2-yl)-2,3-dihydro-1H-spir...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249869BDBM50249869(3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NPY Y2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249869BDBM50249869(3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NPY Y1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249869BDBM50249869(3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NPY Y4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed