Compile Data Set for Download or QSAR
Report error Found 80 Enz. Inhib. hit(s) with all data for entry = 50004210
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480105BDBM50480105(CHEMBL496201)
Affinity DataIC50: 1nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480108BDBM50480108(CHEMBL496009)
Affinity DataIC50: 1nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480091BDBM50480091(CHEMBL523753)
Affinity DataIC50: 6nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480092BDBM50480092(CHEMBL522072)
Affinity DataIC50: 7nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480123BDBM50480123(CHEMBL496612)
Affinity DataIC50: 7nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480112BDBM50480112(CHEMBL496020)
Affinity DataIC50: 8nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480093BDBM50480093(CHEMBL487717)
Affinity DataIC50: 10nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480094BDBM50480094(CHEMBL496414)
Affinity DataIC50: 12nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480124BDBM50480124(CHEMBL496202)
Affinity DataIC50: 12nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480095BDBM50480095(CHEMBL501686)
Affinity DataIC50: 14nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480127BDBM50480127(CHEMBL496203)
Affinity DataIC50: 16nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480096BDBM50480096(CHEMBL524068)
Affinity DataIC50: 17nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480097BDBM50480097(CHEMBL498025)
Affinity DataIC50: 21nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480098BDBM50480098(CHEMBL496185)
Affinity DataIC50: 22nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480099BDBM50480099(CHEMBL498459)
Affinity DataIC50: 23nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480116BDBM50480116(CHEMBL522724)
Affinity DataIC50: 23nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29701BDBM29701(Pyridoimidazolone, 5a)
Affinity DataIC50: 23nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480100BDBM50480100(CHEMBL487718)
Affinity DataIC50: 24nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480115BDBM50480115(CHEMBL496019)
Affinity DataIC50: 25nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480101BDBM50480101(CHEMBL521725)
Affinity DataIC50: 30nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480102BDBM50480102(CHEMBL524801)
Affinity DataIC50: 37nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480103BDBM50480103(CHEMBL498112)
Affinity DataIC50: 37nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480107BDBM50480107(CHEMBL496081)
Affinity DataIC50: 37nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480121BDBM50480121(CHEMBL526838)
Affinity DataIC50: 37nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480104BDBM50480104(CHEMBL498024)
Affinity DataIC50: 47nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480125BDBM50480125(CHEMBL523905)
Affinity DataIC50: 56nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480110BDBM50480110(CHEMBL496073)
Affinity DataIC50: 79nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480109BDBM50480109(CHEMBL495801)
Affinity DataIC50: 90nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480119BDBM50480119(CHEMBL523229)
Affinity DataIC50: 106nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480126BDBM50480126(CHEMBL487719)
Affinity DataIC50: 156nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480111BDBM50480111(CHEMBL489856)
Affinity DataIC50: 167nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480103BDBM50480103(CHEMBL498112)
Affinity DataIC50: 214nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480121BDBM50480121(CHEMBL526838)
Affinity DataIC50: 214nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480120BDBM50480120(CHEMBL498113)
Affinity DataIC50: 220nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480095BDBM50480095(CHEMBL501686)
Affinity DataIC50: 346nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480129BDBM50480129(CHEMBL523907)
Affinity DataIC50: 430nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480101BDBM50480101(CHEMBL521725)
Affinity DataIC50: 559nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480093BDBM50480093(CHEMBL487717)
Affinity DataIC50: 600nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480105BDBM50480105(CHEMBL496201)
Affinity DataIC50: 610nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480106BDBM50480106(CHEMBL498458)
Affinity DataIC50: 638nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480099BDBM50480099(CHEMBL498459)
Affinity DataIC50: 770nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480096BDBM50480096(CHEMBL524068)
Affinity DataIC50: 810nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480107BDBM50480107(CHEMBL496081)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480123BDBM50480123(CHEMBL496612)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480108BDBM50480108(CHEMBL496009)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480097BDBM50480097(CHEMBL498025)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480100BDBM50480100(CHEMBL487718)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480106BDBM50480106(CHEMBL498458)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480091BDBM50480091(CHEMBL523753)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480111BDBM50480111(CHEMBL489856)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
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