Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50031611
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316213BDBM50316213(4-((3-(2-(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,...)
Affinity DataIC50: 0.400nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316210BDBM50316210(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50: 4nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316212BDBM50316212(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50: 4nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316205BDBM50316205(N-(2-(3-(2-(diisopropylamino)ethyl)ureido)ethyl)-6...)
Affinity DataIC50: 5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316211BDBM50316211(N-(2-(3-(4-((diethylamino)methyl)benzyl)ureido)eth...)
Affinity DataIC50: 5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316202BDBM50316202(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50: 5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316209BDBM50316209(N-(2-(3-benzylureido)ethyl)-6-(2,2-diphenylethylam...)
Affinity DataIC50: 6nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50233816BDBM50233816(1-(2-(cyclopentyl(isopropyl)amino)ethyl)-3-((6-(2,...)
Affinity DataIC50: 6nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316204BDBM50316204(N-(2-(3-(2-(cyclopentyl(isopropyl)amino)ethyl)urei...)
Affinity DataIC50: 7nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316206BDBM50316206(N-(2-(3-(2-(3,4-dihydroisoquinolin-2(1H)-yl)ethyl)...)
Affinity DataIC50: 10nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316208BDBM50316208(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50: 10nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50233809BDBM50233809(1-((6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-...)
Affinity DataIC50: 17nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316203BDBM50316203(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)te...)
Affinity DataIC50: 45nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50233810BDBM50233810(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)te...)
Affinity DataIC50: 65nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316207BDBM50316207(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50: 305nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed