Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 3356
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31801BDBM31801(2-aminobenzimidazole deriv., 12)
Affinity DataKi:  7nM ΔG°:  -46.2kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31800BDBM31800(2-aminobenzimidazole deriv., 11)
Affinity DataKi:  47nM ΔG°:  -41.5kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31798BDBM31798(2-aminobenzimidazole deriv., 9)
Affinity DataKi:  400nM ΔG°:  -36.3kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31799BDBM31799(2-aminobenzimidazole deriv., 10)
Affinity DataKi:  510nM ΔG°:  -35.7kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31795BDBM31795(2-aminobenzimidazole deriv., 6)
Affinity DataKi:  9.80E+3nM ΔG°:  -28.4kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31794BDBM31794(CHEMBL269158 | 6-chloro-1H-benzo[d]imidazol-2-amin...)
Affinity DataKi:  1.06E+4nM ΔG°:  -28.2kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31791BDBM31791(2-aminobenzothiazole deriv., 2)
Affinity DataKi:  2.11E+4nM ΔG°:  -26.5kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31797BDBM31797(2-aminobenzimidazole deriv., 8)
Affinity DataKi:  2.39E+4nM ΔG°:  -26.2kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31793BDBM31793(2-aminobenzothiazole deriv., 3)
Affinity DataKi:  1.41E+5nM ΔG°:  -21.8kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 31796BDBM31796(2-aminobenzimidazole deriv., 7)
Affinity DataKi: >2.00E+5nM ΔG°: >-21.0kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMed
TargetPteridine reductase(Trypanosoma brucei brucei)
University of Dundee

LigandChemical structure of BindingDB Monomer ID 7960BDBM7960(CHEMBL305513 | JMC524454 Compound 5 | 1H-1,3-benzo...)
Affinity DataKi:  2.88E+5nM ΔG°:  -20.1kJ/molepH: 6.0 T: 2°CAssay Description:TbPTR1 activity was measured in 96-well microtiter plates via reduction of cytochrome c (cytc) as a result of the enzymatic production of tetrahydrob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)