Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50030542
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297767BDBM50297767((R)-1-(2-(5-(4-(ethylsulfonyl)phenoxy)-2-(pyridin-...)
Affinity DataEC50:  360nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297767BDBM50297767((R)-1-(2-(5-(4-(ethylsulfonyl)phenoxy)-2-(pyridin-...)
Affinity DataEC50:  630nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297768BDBM50297768(1-(2-(5-(3-fluorophenoxy)-2-(pyridin-2-yl)-1H-benz...)
Affinity DataEC50:  930nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297785BDBM50297785(1-(2-(5-(4-fluorophenoxy)-2-(pyridin-2-yl)-1H-benz...)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297769BDBM50297769(1-(2-(5-phenoxy-2-(pyridin-2-yl)-1H-benzo[d]imidaz...)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297770BDBM50297770(1-(2-(5-(4-(methylsulfonyl)phenoxy)-2-(pyridin-2-y...)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297771BDBM50297771(1-(2-(5-(biphenyl-4-yloxy)-2-(pyridin-2-yl)-1H-ben...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297772BDBM50297772(1-(2-(5-(4-(isopropylsulfonyl)phenoxy)-2-(pyridin-...)
Affinity DataEC50:  1.50E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297773BDBM50297773(4-(6-(1-acetylpyrrolidin-2-yl)-2-(pyridin-2-yl)-1H...)
Affinity DataEC50:  1.60E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297774BDBM50297774(1-(2-(5-(4-methoxyphenoxy)-2-(pyridin-2-yl)-1H-ben...)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297777BDBM50297777(1-(2-(5-(4-nitrophenoxy)-2-(pyridin-2-yl)-1H-benzo...)
Affinity DataEC50:  1.90E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297775BDBM50297775(3-(6-(1-acetylpyrrolidin-2-yl)-2-(pyridin-2-yl)-1H...)
Affinity DataEC50:  1.90E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297776BDBM50297776(4-(6-(1-acetylpyrrolidin-2-yl)-2-(pyridin-2-yl)-1H...)
Affinity DataEC50:  1.90E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297779BDBM50297779(1-(2-(5-(3-methoxyphenoxy)-2-(pyridin-2-yl)-1H-ben...)
Affinity DataEC50:  2.40E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297780BDBM50297780(ethyl 4-(6-(1-acetylpyrrolidin-2-yl)-2-(pyridin-2-...)
Affinity DataEC50:  2.70E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297781BDBM50297781(1-(2-(5-(2-fluorophenoxy)-2-(pyridin-2-yl)-1H-benz...)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297786BDBM50297786(ethyl 2-(5-(4-fluorophenoxy)-2-(pyridin-2-yl)-1H-b...)
Affinity DataEC50:  5.47E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297787BDBM50297787(1-(2-(5-(4-fluorophenoxy)-2-(pyridin-2-yl)-1H-benz...)
Affinity DataEC50:  6.10E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297782BDBM50297782(1-(2-(5-(biphenyl-3-yloxy)-2-(pyridin-2-yl)-1H-ben...)
Affinity DataEC50:  7.40E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297783BDBM50297783(1-(2-(5-(2-methoxyphenoxy)-2-(pyridin-2-yl)-1H-ben...)
Affinity DataEC50:  9.60E+3nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297788BDBM50297788(5-(4-fluorophenoxy)-6-(1-(methylsulfonyl)pyrrolidi...)
Affinity DataEC50:  1.91E+4nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297784BDBM50297784(2-(6-(1-acetylpyrrolidin-2-yl)-2-(pyridin-2-yl)-1H...)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297789BDBM50297789(N-ethyl-2-(5-(4-fluorophenoxy)-2-(pyridin-2-yl)-1H...)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297790BDBM50297790((2-(5-(4-fluorophenoxy)-2-(pyridin-2-yl)-1H-benzo[...)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed