Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50030749
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300863BDBM50300863(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-3,...)
Affinity DataIC50: 79.8nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249489BDBM50249489(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-3,...)
Affinity DataIC50: 97.9nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300862BDBM50300862(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-...)
Affinity DataIC50: 117nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300861BDBM50300861(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-3-...)
Affinity DataIC50: 119nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300860BDBM50300860(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-be...)
Affinity DataIC50: 163nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300859BDBM50300859(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-...)
Affinity DataIC50: 185nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300858BDBM50300858(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300857BDBM50300857(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-...)
Affinity DataIC50: 224nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300856BDBM50300856(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-...)
Affinity DataIC50: 251nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300855BDBM50300855(N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-2-...)
Affinity DataIC50: 876nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232973BDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
University of Leipzig

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300854BDBM50300854(N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-3,4,5-triet...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed