Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50004228
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450704BDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50: 1nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450704BDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50: 2nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50008057BDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50008057BDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 4nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480378BDBM50480378(CHEMBL563608)
Affinity DataIC50: 7nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50008057BDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 8nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480379BDBM50480379(SNX-5422 | CHEMBL553939)
Affinity DataIC50: 11nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480379BDBM50480379(SNX-5422 | CHEMBL553939)
Affinity DataIC50: 13nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480378BDBM50480378(CHEMBL563608)
Affinity DataIC50: 14nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480378BDBM50480378(CHEMBL563608)
Affinity DataIC50: 16nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50008057BDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 32nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450704BDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50: 41nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480374BDBM50480374(CHEMBL560955)
Affinity DataIC50: 46nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480379BDBM50480379(SNX-5422 | CHEMBL553939)
Affinity DataIC50: 61nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480372BDBM50480372(CHEMBL562990)
Affinity DataIC50: 490nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480395BDBM50480395(CHEMBL559840)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480380BDBM50480380(CHEMBL552300)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480373BDBM50480373(CHEMBL563335)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480379BDBM50480379(SNX-5422 | CHEMBL553939)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480371BDBM50480371(CHEMBL554288)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480378BDBM50480378(CHEMBL563608)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480393BDBM50480393(CHEMBL563500)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480368BDBM50480368(CHEMBL559642)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480369BDBM50480369(CHEMBL557479)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480370BDBM50480370(CHEMBL562929)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450704BDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480392BDBM50480392(CHEMBL556391)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480398BDBM50480398(CHEMBL560156)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480394BDBM50480394(CHEMBL561019)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480375BDBM50480375(CHEMBL564211)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480402BDBM50480402(CHEMBL561497)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480376BDBM50480376(CHEMBL558876)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480381BDBM50480381(CHEMBL538683)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480390BDBM50480390(CHEMBL549744)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480400BDBM50480400(CHEMBL557478)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480382BDBM50480382(CHEMBL565035)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480391BDBM50480391(CHEMBL562038)
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480386BDBM50480386(CHEMBL562037)
Affinity DataIC50: 1.47E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480388BDBM50480388(CHEMBL564702)
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480383BDBM50480383(CHEMBL561637)
Affinity DataIC50: 1.84E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480377BDBM50480377(CHEMBL551293)
Affinity DataIC50: 2.03E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480396BDBM50480396(CHEMBL551699)
Affinity DataIC50: 2.26E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480399BDBM50480399(CHEMBL564559)
Affinity DataIC50: 2.29E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480401BDBM50480401(CHEMBL561224)
Affinity DataIC50: 2.48E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480387BDBM50480387(CHEMBL549543)
Affinity DataIC50: 2.64E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480384BDBM50480384(CHEMBL550139)
Affinity DataIC50: 4.18E+5nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480385BDBM50480385(CHEMBL561498)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480389BDBM50480389(CHEMBL556878)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50480397BDBM50480397(CHEMBL552094)
Affinity DataIC50: 7.00E+6nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed