Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 8082
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232987BDBM232987((E)-3-(4-(4-methoxybenzyloxy)-3-methoxyphenyl)-N-h...)
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232991BDBM232991((E)-3-(4-(3,4,5-trimethoxybenzyloxy)-3-methoxyphen...)
Affinity DataIC50: 7.70E+3nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232981BDBM232981((E)-N-hydroxy-3-(3-methoxy-4-(thiophen-2-ylmethoxy...)
Affinity DataIC50: 1.11E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232980BDBM232980((E)-N-hydroxy-3-(4-(thiophen-2-ylmethoxy)phenyl)ac...)
Affinity DataIC50: 1.25E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232985BDBM232985((E)-3-(4-(4-methylbenzyloxy)-3-methoxyphenyl)-N-hy...)
Affinity DataIC50: 1.33E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232979BDBM232979((E)-3-(4-(benzyloxy)-3-methoxyphenyl)-N-hydroxyacr...)
Affinity DataIC50: 1.34E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232986BDBM232986((E)-3-(4-(4-methoxybenzyloxy)phenyl)-N-hydroxyacry...)
Affinity DataIC50: 1.45E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232978BDBM232978((E)-3-(4-(benzyloxy)phenyl)-N-hydroxyacrylamide (4...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232990BDBM232990((E)-3-(4-(3,4,5-trimethoxybenzyloxy)phenyl)-N-hydr...)
Affinity DataIC50: 2.06E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232983BDBM232983((E)-N-hydroxy-3-(3-methoxy-4-(pyridin-3-ylmethoxy)...)
Affinity DataIC50: 2.16E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232984BDBM232984((E)-3-(4-(4-methylbenzyloxy)phenyl)-N-hydroxyacryl...)
Affinity DataIC50: 2.35E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232989BDBM232989((E)-3-(4-(4-chlorobenzyloxy)-3-methoxyphenyl)-N-hy...)
Affinity DataIC50: 2.78E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232982BDBM232982((E)-N-hydroxy-3-(4-(pyridin-3-ylmethoxy)phenyl)acr...)
Affinity DataIC50: 2.95E+4nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

LigandChemical structure of BindingDB Monomer ID 232988BDBM232988((E)-3-(4-(4-chlorobenzyloxy)phenyl)-N-hydroxyacryl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed