Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50033481
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346176(2-(pyridin-3-yl)quinuclidine dihydrochloride | CHE...)
Affinity DataKi:  69nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346172(2-(pyridin-3-ylmethyl)quinuclidine bis(2,2,2-trifl...)
Affinity DataKi:  449nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346168((R)-3-(pyrrolidin-2-ylethynyl)pyridine hemigalacta...)
Affinity DataKi:  733nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346177(2-(pyrimidin-5-yl)quinuclidine bis(2,2,2-trifluoro...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346178(8-methyl-3-(pyridin-3-yl)-8-azabicyclo[3.2.1]oct-2...)
Affinity DataKi:  2.11E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346173(2-(pyrimidin-5-ylmethyl)quinuclidine bis(2,2,2-tri...)
Affinity DataKi:  2.59E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346174((S)-3-(2-(pyrrolidin-3-yl)vinyl)pyridine bis(2,2,2...)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346168((R)-3-(pyrrolidin-2-ylethynyl)pyridine hemigalacta...)
Affinity DataKi:  5.77E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346179(8-methyl-3-(pyrimidin-5-yl)-8-azabicyclo[3.2.1]oct...)
Affinity DataKi:  9.10E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346168((R)-3-(pyrrolidin-2-ylethynyl)pyridine hemigalacta...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346168((R)-3-(pyrrolidin-2-ylethynyl)pyridine hemigalacta...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Mus musculus)
Targacept

Curated by ChEMBL
LigandPNGBDBM50346168((R)-3-(pyrrolidin-2-ylethynyl)pyridine hemigalacta...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in C57BL/6J mouse hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed