Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with all data for entry = 50030564
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50:  47nMAssay Description:Inhibition of ALK5 assessed as inhibition of immobilized Smad3 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Institute Of Pharmacology And Toxicology

Curated by ChEMBL
LigandPNGBDBM50110208(4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1...)
Affinity DataIC50:  94nMAssay Description:Inhibition of ALK5 assessed as inhibition of immobilized Smad3 phosphorylationMore data for this Ligand-Target Pair