Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50030776
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301218((1R,2S)-2-(3-chloro-5-fluorophenylcarbamoyl)cycloh...)
Affinity DataEC50:  2.00E+3nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301219(CHEMBL578988 | cis-2-(3,5-dichlorophenylcarbamoyl)...)
Affinity DataEC50:  740nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301220((1S,2R)-N1-(3,5-dichlorophenyl)cyclohex-4-ene-1,2-...)
Affinity DataEC50:  3.10E+3nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301221((1R,6S)-6-(3,5-dichlorophenylcarbamoyl)cyclohex-3-...)
Affinity DataEC50:  2.70E+3nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301222((1S,2R)-N-(3,5-dichlorophenyl)-2-(1H-tetrazol-5-yl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301229((1R,2S)-2-(phenylcarbamoyl)cyclohexanecarboxylic a...)
Affinity DataEC50: >1.00E+4nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301224((3aR)-2-(3,5-dichlorophenyl)hexahydro-1H-isoindole...)
Affinity DataEC50:  3.30E+3nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301225((1R,2S)-N1-(cyclopropylmethyl)-N2-(3,5-dichlorophe...)
Affinity DataEC50:  1.00E+4nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301226((1S,2R)-N1-(3,5-dichlorophenyl)-N2-propylcyclohexa...)
Affinity DataEC50:  9.60E+3nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301227((1S,2R)-N1-(3,5-dichlorophenyl)-N2-methylcyclohexa...)
Affinity DataEC50:  1.00E+4nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301228((1S,2R)-N1-(3,5-dichlorophenyl)cyclohexane-1,2-dic...)
Affinity DataEC50:  950nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301223((1S,2R)-2-cyano-N-(3,5-dichlorophenyl)cyclohexanec...)
Affinity DataEC50:  2.00E+3nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed