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Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 3490
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35595(pyrazolo pyrimidine, 28)
Affinity DataIC50:  0.0800nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35592(pyrazolo pyrimidine, 24)
Affinity DataIC50:  0.200nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35593(pyrazolo pyrimidine, 25)
Affinity DataIC50:  0.300nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35589(pyrazolo pyrimidine, 21)
Affinity DataIC50:  0.320nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35594(pyrazolo pyrimidine, 27)
Affinity DataIC50:  0.340nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35578(pyrazolo pyrimidine, 10)
Affinity DataIC50:  0.380nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35591(pyrazolo pyrimidine, 23)
Affinity DataIC50:  0.450nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35585(pyrazolo pyrimidine, 18)
Affinity DataIC50:  0.460nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35580(pyrazolo pyrimidine, 13)
Affinity DataIC50:  0.520nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35590(pyrazolo pyrimidine, 22)
Affinity DataIC50:  0.610nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35586(pyrazolo pyrimidine, 26)
Affinity DataIC50:  0.830nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35588(pyrazolo pyrimidine, 20)
Affinity DataIC50:  1nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35584(pyrazolo pyrimidine, 17)
Affinity DataIC50:  1.10nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35579(pyrazolo pyrimidine, 6)
Affinity DataIC50:  1.40nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35577(pyrazolo pyrimidine, 12)
Affinity DataIC50:  1.5nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35583(pyrazolo pyrimidine, 16)
Affinity DataIC50:  2nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35582(pyrazolo pyrimidine, 15)
Affinity DataIC50:  2.10nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35587(pyrazolo pyrimidine, 19)
Affinity DataIC50:  4.30nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35575(pyrazolo pyrimidine, 9)
Affinity DataIC50:  4.60nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35595(pyrazolo pyrimidine, 28)
Affinity DataIC50:  6nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35573(pyrazolo pyrimidine, 7)
Affinity DataIC50:  7nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35572(JMC527081 Compound 5f | pyrazolo pyrimidine, 1)
Affinity DataIC50:  9.60nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35580(pyrazolo pyrimidine, 13)
Affinity DataIC50:  14nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35594(pyrazolo pyrimidine, 27)
Affinity DataIC50:  15nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35593(pyrazolo pyrimidine, 25)
Affinity DataIC50:  18nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35581(pyrazolo pyrimidine, 14)
Affinity DataIC50:  22nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35579(pyrazolo pyrimidine, 6)
Affinity DataIC50:  23nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35592(pyrazolo pyrimidine, 24)
Affinity DataIC50:  35nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35578(pyrazolo pyrimidine, 10)
Affinity DataIC50:  41nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35576(pyrazolo pyrimidine, 11)
Affinity DataIC50:  46nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35572(JMC527081 Compound 5f | pyrazolo pyrimidine, 1)
Affinity DataIC50:  47nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35585(pyrazolo pyrimidine, 18)
Affinity DataIC50:  100nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35583(pyrazolo pyrimidine, 16)
Affinity DataIC50:  149nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35584(pyrazolo pyrimidine, 17)
Affinity DataIC50:  209nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35581(pyrazolo pyrimidine, 14)
Affinity DataIC50:  211nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35582(pyrazolo pyrimidine, 15)
Affinity DataIC50:  225nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35577(pyrazolo pyrimidine, 12)
Affinity DataIC50:  284nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35573(pyrazolo pyrimidine, 7)
Affinity DataIC50:  404nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35589(pyrazolo pyrimidine, 21)
Affinity DataIC50:  490nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35590(pyrazolo pyrimidine, 22)
Affinity DataIC50:  505nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35586(pyrazolo pyrimidine, 26)
Affinity DataIC50:  548nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35576(pyrazolo pyrimidine, 11)
Affinity DataIC50:  631nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35591(pyrazolo pyrimidine, 23)
Affinity DataIC50:  661nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35588(pyrazolo pyrimidine, 20)
Affinity DataIC50:  681nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35575(pyrazolo pyrimidine, 9)
Affinity DataIC50:  801nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35587(pyrazolo pyrimidine, 19)
Affinity DataIC50:  1.03E+3nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM35574(pyrazolo pyrimidine, 8)
Affinity DataIC50:  2.01E+3nMT: 25°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

LigandPNGBDBM35574(pyrazolo pyrimidine, 8)
Affinity DataIC50:  2.45E+3nMpH: 7.4 T: 23°CAssay Description:The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed