Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50030783
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301329BDBM50301329(5-chloro-6-(4-((2S)-1-(4-chlorobenzyl)-2-methylpip...)
Affinity DataKi:  16nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301335BDBM50301335(5-chloro-6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)pip...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at recombinant human CXCR3 receptor expressed in Ba/F3 cells assessed as hMIG-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301330BDBM50301330(5-chloro-6-(4-((2S)-1-(4-chlorobenzyl)-2-methylpip...)
Affinity DataKi:  32nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301351BDBM50301351(5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)pi...)
Affinity DataKi:  35nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301335BDBM50301335(5-chloro-6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)pip...)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at recombinant human CXCR3 receptor expressed in Ba/F3 cells assessed as hIP10-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301340BDBM50301340(5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)pi...)
Affinity DataKi:  70nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301341BDBM50301341(6-(4-(1-(4-bromobenzyl)piperidin-4-yl)piperazin-1-...)
Affinity DataKi:  85nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301335BDBM50301335(5-chloro-6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)pip...)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at recombinant human CXCR3 receptor expressed in Ba/F3 cells assessed as hI-TAC-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301328BDBM50301328((R)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-y...)
Affinity DataKi:  86nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301326BDBM50301326(5-chloro-6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)pip...)
Affinity DataKi:  90nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301335BDBM50301335(5-chloro-6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)pip...)
Affinity DataKi:  110nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301344BDBM50301344(5-chloro-6-(4-(1-(4-methoxybenzyl)piperidin-4-yl)p...)
Affinity DataKi:  120nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301348BDBM50301348(N-benzyl-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidi...)
Affinity DataKi:  140nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301342BDBM50301342(5-chloro-6-(4-(1-(4-fluorobenzyl)piperidin-4-yl)pi...)
Affinity DataKi:  160nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301339BDBM50301339(5-chloro-6-(4-(1-(4-cyanobenzoyl)piperidin-4-yl)pi...)
Affinity DataKi:  320nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301325BDBM50301325(3-chloro-4-(4-(1-(4-chlorobenzyl)piperidin-4-yl)pi...)
Affinity DataKi:  330nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301347BDBM50301347(N-butyl-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin...)
Affinity DataKi:  370nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301350BDBM50301350(5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)pi...)
Affinity DataKi:  410nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301349BDBM50301349(5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)pi...)
Affinity DataKi:  470nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301343BDBM50301343(5-chloro-N-(2-phenoxyethyl)-6-(4-(1-(4-(trifluorom...)
Affinity DataKi:  510nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301346BDBM50301346(5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)pi...)
Affinity DataKi:  560nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301354BDBM50301354(1-(5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl...)
Affinity DataKi:  870nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301336BDBM50301336(6-(4-(1-benzylpiperidin-4-yl)piperazin-1-yl)-5-chl...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301352BDBM50301352(N-(5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301334BDBM50301334(5-chloro-6-(4-(3-((4-chlorophenyl)(methyl)amino)pr...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301331BDBM50301331(5-chloro-6-(1'-(4-chlorobenzyl)-4,4'-bipiperidin-1...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301345BDBM50301345(5-chloro-6-(4-(1-(4-(dimethylamino)benzyl)piperidi...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301355BDBM50301355(1-(5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl...)
Affinity DataKi:  3.70E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301324BDBM50301324(3,4-dichloro-N-((5-chloro-6-(4-(1-(4-chlorobenzyl)...)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301337BDBM50301337(5-chloro-6-(4-(1-(3-cyanobenzyl)piperidin-4-yl)pip...)
Affinity DataKi:  4.10E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301332BDBM50301332(5-chloro-6-(4-(4-(4-chlorobenzyl)piperazin-1-yl)pi...)
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301327BDBM50301327(6-(4-(1-(4-cyanobenzyl)piperidin-4-yl)piperazin-1-...)
Affinity DataKi:  7.20E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301338BDBM50301338(5-chloro-6-(4-(1-(2-cyanobenzyl)piperidin-4-yl)pip...)
Affinity DataKi:  8.90E+3nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301333BDBM50301333(5-chloro-6-((2-((1-(4-chlorobenzyl)piperidin-4-yl)...)
Affinity DataKi:  2.30E+4nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301353BDBM50301353(1-(5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed