BindingDB PrimarySearch

Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50038972

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301365(CHEMBL570365 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 33nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 35nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301359(CHEMBL570846 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 44nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301358(CHEMBL568729 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 50nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 53nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 110nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301362(4-(2-methoxyethylamino)-N-(5-(7-methoxyquinolin-4-...)

IC50: 120nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301363(1-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)

IC50: 170nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301357(CHEMBL572237 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 200nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301366(5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)

IC50: 310nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301366(5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)

IC50: 310nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301367(CHEMBL570381 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...)

IC50: 430nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Interferon-induced, double-stranded RNA-activated protein kinase(Human)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.00E+3nMAssay Description:Inhibition of PKRMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301368(CHEMBL570189 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...)

IC50: 1.00E+3nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Eukaryotic translation initiation factor 2-alpha kinase 3(Human)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.00E+3nMAssay Description:Inhibition of PEKMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Tyrosine-protein kinase JAK3(Human)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.00E+3nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Tyrosine-protein kinase JAK2(Human)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.00E+3nMAssay Description:Inhibition of Jak2More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Tyrosine-protein kinase JAK1(Human)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.00E+3nMAssay Description:Inhibition of Jak1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Non-receptor tyrosine-protein kinase TYK2(Human)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.00E+3nMAssay Description:Inhibition of TYK2More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 1.12E+3nMAssay Description:Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301359(CHEMBL570846 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 1.30E+3nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301361(CHEMBL570647 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 1.50E+3nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301358(CHEMBL568729 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 1.80E+3nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301366(5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)

IC50: 1.80E+3nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Human)
Amgen

Curated by ChEMBL

BDBM50301360(CHEMBL570643 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 2.80E+3nMAssay Description:Inhibition of human Pyk2 by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 1.70E+4nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301361(CHEMBL570647 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: 1.80E+4nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301368(CHEMBL570189 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...)

IC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301367(CHEMBL570381 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...)

IC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301365(CHEMBL570365 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301363(1-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...)

IC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301362(4-(2-methoxyethylamino)-N-(5-(7-methoxyquinolin-4-...)

IC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301357(CHEMBL572237 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Focal adhesion kinase 1(Human)
Amgen

Curated by ChEMBL

BDBM50301360(CHEMBL570643 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

IC50: >1.25E+5nMAssay Description:Inhibition of human FAK by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL

BDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

EC50: 10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in alkaline phosphatase levelMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL

BDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

EC50: 10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium levelMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

EC50: 10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in osteocalcin levelMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

EC50: 10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in alkaline phosphatase levelMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL

BDBM50301364(CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

EC50: 10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in osteocalcin levelMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Protein-tyrosine kinase 2-beta(Mouse)
Amgen

Curated by ChEMBL

BDBM50301356(CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...)

EC50: 10nMAssay Description:Inhibition of mouse Pyk2 in MC3TC3 cells assessed as increase in calcium levelMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed