Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50031299
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310682((S)-2-amino-N-((S)-1-cyano-2-(5-phenylthiophen-2-y...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310681((S)-2-amino-N-((S)-2-(benzo[d]thiazol-2-yl)-1-cyan...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310678((S)-2-amino-N-((S)-1-cyano-2-phenylethyl)-3-(thiop...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310680((S)-2-amino-N-((S)-1-cyano-2-(naphthalen-2-yl)ethy...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310700((2S,4R)-N-((S)-1-cyano-2-phenylethyl)-4-(methylthi...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310676((S)-2-amino-N-((S)-1-cyano-2,2-diphenylethyl)-3-(t...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310677((S)-2-amino-N-((S)-1-cyano-2-cyclohexylethyl)-3-(t...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310673((S)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310699((2S,4R)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-p...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310679((S)-2-amino-N-((S)-1-cyano-3-phenylpropyl)-3-(thio...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310684((S)-2-amino-N-(1-cyanocyclopropyl)-3-(thiophen-2-y...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310674((S)-2-amino-N-(cyanomethyl)-3-(thiophen-2-yl)propa...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310689(CHEMBL1080786 | cis-(S)-2-amino-N-((1S,2S)-1-cyano...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310696((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-(methylthi...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310687((2S)-2-amino-N-(1-cyano-2,2-dimethylcyclopropyl)-3...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310694((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoropyrr...)
Affinity DataIC50:  133nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310705(CHEMBL1077666 | Cis-(2S,4S)-N-(2-benzyl-1-cyanocyc...)
Affinity DataIC50:  192nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310705(CHEMBL1077666 | Cis-(2S,4S)-N-(2-benzyl-1-cyanocyc...)
Affinity DataIC50:  192nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310669((S)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310675((S)-2-amino-N-((S)-1-cyano-2-methylpropyl)-3-(thio...)
Affinity DataIC50:  215nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310698((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-(ethylthio...)
Affinity DataIC50:  271nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310672((S)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310702((2S,4S)-N-(1-cyanocyclopropyl)-4-(methylthio)pyrro...)
Affinity DataIC50:  336nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310693((2S,4S)-4-chloro-N-((S)-1-cyano-2-phenylethyl)pyrr...)
Affinity DataIC50:  495nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310704(CHEMBL1078356 | Cis-(2S,4S)-N-(2-benzyl-1-cyanocyc...)
Affinity DataIC50:  523nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310704(CHEMBL1078356 | Cis-(2S,4S)-N-(2-benzyl-1-cyanocyc...)
Affinity DataIC50:  523nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310670((R)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)
Affinity DataIC50:  630nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310701((2S,4S)-N-(1-cyanocyclopropyl)-4-fluoropyrrolidine...)
Affinity DataIC50:  880nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310692((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-methoxypyr...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310688(CHEMBL1081148 | trans-(+/-)-(2S)-2-amino-N-(1-cyan...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310685((S)-2-amino-N-(2-cyanopropan-2-yl)-3-(thiophen-2-y...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310671((S)-2-amino-N-((S)-1-cyano-2-(1H-indol-3-yl)ethyl)...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310686((S)-2-amino-N-(1-cyanocyclobutyl)-3-(thiophen-2-yl...)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310703((2S,4S)-N-((1S,2S)-1-cyano-2-phenylcyclopropyl)-4-...)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310691((2S,4S)-N-((S)-1-cyano-2-phenylethyl)-4-methylpyrr...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310697((S)-N-((S)-1-cyano-2-(4-(methylthio)phenyl)ethyl)p...)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310683((S)-2-amino-N-((S)-1-cyano-2,2-dimethylpropyl)-3-(...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50186092((S)-N-((S)-1-cyano-2-phenylethyl)pyrrolidine-2-car...)
Affinity DataIC50:  4.81E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310695((S)-N-((S)-1-cyano-2-(4-fluorophenyl)ethyl)pyrroli...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310668((S)-N-(2-(1H-indol-3-yl)ethyl)-2-amino-4-(methylth...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-cathepsin H(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cathepsin HMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloblastin(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Proteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50310690(CHEMBL1078411 | Cis-(S)-2-amino-N-((1R,2R)-1-cyano...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed