Compile Data Set for Download or QSAR
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Found 12 Enz. Inhib. hit(s) with all data for entry = 50030795
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301551(CHEMBL568327 | trans-methyl 4-(3-(2-(4-(trifluorom...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301549(CHEMBL567884 | trans-2-(5-(4-chlorophenyl)-4,5-dih...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301550(CHEMBL568105 | trans-2-(5-(3-chlorophenyl)-4,5-dih...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301548(CHEMBL568102 | trans-N-(4-(trifluoromethoxy)benzyl...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301546(CHEMBL568322 | trans-2-(5-phenyl-4,5-dihydrooxazol...)
Affinity DataIC50:  620nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301552(CHEMBL585731 | trans-methyl 3-(3-(2-(4-(trifluorom...)
Affinity DataIC50:  710nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301547(CHEMBL569285 | trans-2-(5-phenyl-4,5-dihydroisoxaz...)
Affinity DataIC50:  780nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178861((1R,2R)-N1-methyl-N1-((2'-sulfamoylbiphenyl-4-yl)m...)
Affinity DataIC50:  830nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301553(CHEMBL584716 | trans-2-(5-methyl-5-phenyl-4,5-dihy...)
Affinity DataIC50:  960nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301545(CHEMBL565327 | trans-2-(4-(4-chlorophenyl)-4,5-dih...)
Affinity DataIC50:  970nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301555(CHEMBL572352 | trans-N-(4-isopropoxybenzyl)-2-(5-m...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301554(CHEMBL584719 | trans-2-(5-methyl-5-phenyl-4,5-dihy...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed