Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50030805
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301747(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(...)
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301739(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301747(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  1.60nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301739(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301749(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(...)
Affinity DataKi:  3.80nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301746(5-(4-chlorophenyl)-3-(1-cyclohexyl-1H-imidazol-4-y...)
Affinity DataKi:  4.70nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301743(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301745(5-(4-chlorophenyl)-3-(1-cyclobutyl-1H-imidazol-4-y...)
Affinity DataKi:  5nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301751(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-iso...)
Affinity DataKi:  5.20nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301738(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301752(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(2-iso...)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301748(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-cyclopr...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataKi:  7.60nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301748(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-cyclopr...)
Affinity DataKi:  7.90nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301746(5-(4-chlorophenyl)-3-(1-cyclohexyl-1H-imidazol-4-y...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301743(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...)
Affinity DataKi:  9nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301738(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...)
Affinity DataKi:  9nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301752(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(2-iso...)
Affinity DataKi:  9.5nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301751(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-iso...)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301745(5-(4-chlorophenyl)-3-(1-cyclobutyl-1H-imidazol-4-y...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301744(3-(1-tert-butyl-1H-imidazol-4-yl)-5-(4-chloropheny...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301740(3-(1-benzyl-1H-imidazol-4-yl)-5-(4-chlorophenyl)-1...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301736((4-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-me...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301749(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301742(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-eth...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301741(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301750(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(5-isoprop...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301737(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-eth...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed