Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50030805
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301747BDBM50301747(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(...)
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301739BDBM50301739(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21278BDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301747BDBM50301747(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21278BDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  1.60nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301739BDBM50301739(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301749BDBM50301749(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(...)
Affinity DataKi:  3.80nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301746BDBM50301746(5-(4-chlorophenyl)-3-(1-cyclohexyl-1H-imidazol-4-y...)
Affinity DataKi:  4.70nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301743BDBM50301743(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301745BDBM50301745(5-(4-chlorophenyl)-3-(1-cyclobutyl-1H-imidazol-4-y...)
Affinity DataKi:  5nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301751BDBM50301751(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-iso...)
Affinity DataKi:  5.20nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301735BDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301738BDBM50301738(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301752BDBM50301752(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(2-iso...)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301748BDBM50301748(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-cyclopr...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301735BDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataKi:  7.60nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301748BDBM50301748(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-cyclopr...)
Affinity DataKi:  7.90nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301746BDBM50301746(5-(4-chlorophenyl)-3-(1-cyclohexyl-1H-imidazol-4-y...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301743BDBM50301743(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...)
Affinity DataKi:  9nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301738BDBM50301738(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-iso...)
Affinity DataKi:  9nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301751BDBM50301751(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-iso...)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301752BDBM50301752(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(2-iso...)
Affinity DataKi:  9.5nMAssay Description:Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301745BDBM50301745(5-(4-chlorophenyl)-3-(1-cyclobutyl-1H-imidazol-4-y...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301740BDBM50301740(3-(1-benzyl-1H-imidazol-4-yl)-5-(4-chlorophenyl)-1...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301744BDBM50301744(3-(1-tert-butyl-1H-imidazol-4-yl)-5-(4-chloropheny...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301749BDBM50301749(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-3-(...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301736BDBM50301736((4-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-me...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301742BDBM50301742(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(1-eth...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301741BDBM50301741(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301750BDBM50301750(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(5-isoprop...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301737BDBM50301737(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-(5-eth...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]SR141716A from rat brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301735BDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301735BDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301735BDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301735BDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50301735BDBM50301735(1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-(1-isoprop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed