Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50035867
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368060BDBM50368060(CHEMBL1907695)
Affinity DataKi:  0.0230nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368067BDBM50368067(CHEMBL1907702)
Affinity DataKi:  0.0330nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007517BDBM50007517(CHEMBL76402 | 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylme...)
Affinity DataKi:  0.0640nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368065BDBM50368065(CHEMBL1907692)
Affinity DataKi:  0.0870nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007518BDBM50007518(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
Affinity DataKi:  0.120nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.330nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007534BDBM50007534(3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydrox...)
Affinity DataKi:  0.550nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010724BDBM50010724(CHEMBL305916 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-6...)
Affinity DataKi:  0.75nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368067BDBM50368067(CHEMBL1907702)
Affinity DataIC50: 0.770nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007518BDBM50007518(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
Affinity DataIC50: 0.920nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005118BDBM50005118(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007517BDBM50007517(CHEMBL76402 | 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylme...)
Affinity DataIC50: 1.40nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368065BDBM50368065(CHEMBL1907692)
Affinity DataIC50: 1.70nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010644BDBM50010644(CHEMBL3085403 | (S)-3-Bromo-N-(1-ethyl-pyrrolidin-...)
Affinity DataIC50: 1.90nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368063BDBM50368063(CHEMBL1907700)
Affinity DataIC50: 2.30nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368060BDBM50368060(CHEMBL1907695)
Affinity DataIC50: 2.40nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368062BDBM50368062(CHEMBL1907915)
Affinity DataKi:  6.5nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81774BDBM81774(Sulpiride-S | CAS_15676-16-1 | Sulpiride-l | SULPI...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368073BDBM50368073(CHEMBL1907690)
Affinity DataKi:  8.40nMAssay Description:Inhibition of [3H]spiperone binding to rat striatal membrane Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010724BDBM50010724(CHEMBL305916 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-6...)
Affinity DataIC50: 8.80nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 12nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007534BDBM50007534(3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydrox...)
Affinity DataIC50: 12nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368059BDBM50368059(CHEMBL1907697)
Affinity DataIC50: 19nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368070BDBM50368070(CHEMBL1907693)
Affinity DataIC50: 21nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005118BDBM50005118(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataIC50: 32nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010640BDBM50010640(CHEMBL3085402 | (S)-3-Amino-5-bromo-N-(1-ethyl-pyr...)
Affinity DataIC50: 33nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368061BDBM50368061(CHEMBL1907694)
Affinity DataIC50: 44nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368071BDBM50368071(CHEMBL1907691)
Affinity DataIC50: 56nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368073BDBM50368073(CHEMBL1907690)
Affinity DataIC50: 67nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368069BDBM50368069(CHEMBL1907698)
Affinity DataIC50: 71nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368062BDBM50368062(CHEMBL1907915)
Affinity DataIC50: 79nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368068BDBM50368068(CHEMBL1907696)
Affinity DataIC50: 205nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81774BDBM81774(Sulpiride-S | CAS_15676-16-1 | Sulpiride-l | SULPI...)
Affinity DataIC50: 210nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368064BDBM50368064(CHEMBL1907701)
Affinity DataIC50: 420nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010655BDBM50010655(CHEMBL16252 | (S)-3-Ethyl-N-(1-ethyl-pyrrolidin-2-...)
Affinity DataIC50: 820nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368066BDBM50368066(CHEMBL1907699)
Affinity DataIC50: 1.75E+3nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368058BDBM50368058(CHEMBL1907703)
Affinity DataIC50: 2.96E+3nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368072BDBM50368072(CHEMBL1907914)
Affinity DataIC50: 6.17E+3nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed