Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50038977
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301928(4-amino-5-chloro-N-((3R,4S)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301927(Norcisapride | CHEMBL1748)
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301928(4-amino-5-chloro-N-((3R,4S)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 159nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 190nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301927(Norcisapride | CHEMBL1748)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 340nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301924(4-amino-5-chloro-N-((3R,4S)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 390nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301928(4-amino-5-chloro-N-((3R,4S)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 410nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301923(4-amino-5-chloro-N-((3R,4S)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 790nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301930(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301922(4-amino-5-chloro-N-((3S,4R)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301927(Norcisapride | CHEMBL1748)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301925(4-amino-5-chloro-N-((3R,4S)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301927(Norcisapride | CHEMBL1748)
Affinity DataEC50:  2.30E+3nMAssay Description:Antagonist activity at human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301920(4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301921(4-amino-5-chloro-N-((3S,4R)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301926(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-me...)
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 3.90E+3nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301926(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-me...)
Affinity DataIC50: 4.50E+3nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301925(4-amino-5-chloro-N-((3R,4S)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301918(4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-me...)
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301926(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-me...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301920(4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 5.10E+3nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301923(4-amino-5-chloro-N-((3R,4S)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 6.10E+3nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301928(4-amino-5-chloro-N-((3R,4S)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 9.90E+3nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301924(4-amino-5-chloro-N-((3R,4S)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301930(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301930(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301918(4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301920(4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301921(4-amino-5-chloro-N-((3S,4R)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301922(4-amino-5-chloro-N-((3S,4R)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301918(4-amino-5-chloro-N-(2-((((1S,2S)-2-hydroxy-2-(3-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301929(4-amino-5-chloro-N-((3S,4R)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301921(4-amino-5-chloro-N-((3S,4R)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301922(4-amino-5-chloro-N-((3S,4R)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301923(4-amino-5-chloro-N-((3R,4S)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301924(4-amino-5-chloro-N-((3R,4S)-1-(((1R,2R)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301925(4-amino-5-chloro-N-((3R,4S)-1-(((1S,2S)-2-hydroxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed