Affinity DataKi: 0.0350nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 670nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 710nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 3.70E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 6.20E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 9.70E+3nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Displacement of [125I]adrenomedullin from human cloned AM2 receptor expressed in B6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair