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Found 22 Enz. Inhib. hit(s) with all data for entry = 50038981
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50108653(1'-benzyl-3-methoxyspiro[3,4-dihydro-1H-isochromen...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302094(1'-butyl-3-methoxyspiro[isochroman-1,4'-piperidine...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302095(3-methoxy-1'-octylspiro[isochroman-1,4'-piperidine...)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302087(CHEMBL568983 | cis-1'-Hexyl-3-methoxy-3,4-dihydros...)
Affinity DataKi:  159nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302088(CHEMBL569123 | trans-1'-hexyl-3-methoxy-3,4.-dihyd...)
Affinity DataKi:  288nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302082(CHEMBL583266 | trans-3-methoxy-1'-(3-phenylpropyl)...)
Affinity DataKi:  376nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302084(CHEMBL570040 | trans-3-methoxy-1'-(4-phenylbutyl)-...)
Affinity DataKi:  392nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302079(CHEMBL572254 | cis-3-Methoxy-1'-(2-phenylethyl)-3,...)
Affinity DataKi:  470nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302086(CHEMBL576497 | trans-1'-butyl-3-methoxy-3,4-dihydr...)
Affinity DataKi:  535nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302080(CHEMBL569823 | trans-3-methoxy-1'-(2-phenylethyl)-...)
Affinity DataKi:  725nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302085(CHEMBL571152 | cis-1'-Butyl-3-methoxy-3,4-dihydros...)
Affinity DataKi:  984nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302089(CHEMBL569109 | cis-3-Methoxy-1'-octyl-3,4-dihydros...)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302083(CHEMBL570039 | cis-3-Methoxy-1'-(4-phenylbutyl)-3,...)
Affinity DataKi:  1.17E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302081(CHEMBL576879 | cis-3-Methoxy-1'-(3-phenylpropyl)-3...)
Affinity DataKi:  1.22E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302097(CHEMBL570925 | trans-1'-benzyl-3-methoxy-3,4-dihyd...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302096(CHEMBL570272 | cis-1'-Benzyl-3-methoxy-3,4-dihydro...)
Affinity DataKi:  1.72E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302091(CHEMBL576904 | cis-1'-Decyl-3-methoxy-3,4-dihydros...)
Affinity DataKi:  2.08E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302090(CHEMBL569110 | trans-3-methoxy-1'-octyl-3,4-dihydr...)
Affinity DataKi:  2.98E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302092(CHEMBL569344 | trans-1'-decyl-3-methoxy-3,4-dihydr...)
Affinity DataKi:  4.36E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed