Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50000866
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007522BDBM50007522(CHEMBL289330 | 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylm...)
Affinity DataIC50: 1.20nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007517BDBM50007517(CHEMBL76402 | 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylme...)
Affinity DataIC50: 1.40nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010728BDBM50010728(CHEMBL75876 | N-(8-Benzyl-8-aza-bicyclo[3.2.1]oct-...)
Affinity DataIC50: 1.70nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010719BDBM50010719(CHEMBL77492 | 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylme...)
Affinity DataIC50: 1.90nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007514BDBM50007514(CHEMBL75842 | N-(1-Benzyl-piperidin-4-yl)-5-bromo-...)
Affinity DataIC50: 5nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010720BDBM50010720(CHEMBL301532 | 5-Bromo-2,3-dihydro-benzofuran-7-ca...)
Affinity DataIC50: 7.20nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010724BDBM50010724(CHEMBL305916 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-6...)
Affinity DataIC50: 8.80nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010727BDBM50010727(CHEMBL76266 | 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylme...)
Affinity DataIC50: 10nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007534BDBM50007534(3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydrox...)
Affinity DataIC50: 12nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005118BDBM50005118(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataIC50: 32nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010723BDBM50010723(CHEMBL74970 | 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylme...)
Affinity DataIC50: 44nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010721BDBM50010721(CHEMBL419832 | 7-Bromo-2,3-dihydro-benzo[1,4]dioxi...)
Affinity DataIC50: 46nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010718BDBM50010718(CHEMBL75447 | 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylme...)
Affinity DataIC50: 46nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010726BDBM50010726(CHEMBL75887 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2,...)
Affinity DataIC50: 52nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452879BDBM50452879(CHEMBL2114141)
Affinity DataIC50: 145nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Astra Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010725BDBM50010725(CHEMBL307491 | 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylm...)
Affinity DataIC50: 8.21E+3nMAssay Description:The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed