Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50039024
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50136674((R)-duloxetine | LY248685 | (3R)-N-methyl-3-(1-nap...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50136674((R)-duloxetine | LY248685 | (3R)-N-methyl-3-(1-nap...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50136674((R)-duloxetine | LY248685 | (3R)-N-methyl-3-(1-nap...)
Affinity DataIC50: 13.2nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304388((S)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304388((S)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataIC50: 25.6nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50136674((R)-duloxetine | LY248685 | (3R)-N-methyl-3-(1-nap...)
Affinity DataKi:  61.3nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304389((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-(naphtha...)
Affinity DataKi:  127nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataIC50: 188nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 227nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 232nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 338nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataIC50: 404nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataKi:  431nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304389((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-(naphtha...)
Affinity DataIC50: 442nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304388((S)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataIC50: 445nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataKi:  525nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50136674((R)-duloxetine | LY248685 | (3R)-N-methyl-3-(1-nap...)
Affinity DataKi:  550nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataKi:  726nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50136674((R)-duloxetine | LY248685 | (3R)-N-methyl-3-(1-nap...)
Affinity DataIC50: 809nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304389((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-(naphtha...)
Affinity DataKi:  857nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataKi:  953nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304389((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-(naphtha...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304389((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-(naphtha...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataKi:  2.38E+3nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304388((S)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304389((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-(naphtha...)
Affinity DataKi:  3.24E+3nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataKi:  3.55E+3nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataKi:  4.60E+3nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataIC50: 6.63E+3nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304388((S)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304393((R)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304388((S)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propyla...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304392((cis)-2-(5-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a...)
Affinity DataKi:  3.91E+4nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304391((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304391((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304391((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304392((cis)-2-(5-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304392((cis)-2-(5-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304391((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304391((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304391((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304392((cis)-2-(5-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304392((cis)-2-(5-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304392((cis)-2-(5-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed