Compile Data Set for Download or QSAR
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Found 19 Enz. Inhib. hit(s) with all data for entry = 50030952
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304417(CHEMBL593656 | CHEMBL593877 | cis-(+/-)-4-(3,4-Dim...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304410(CHEMBL594108 | cis-2-[(E)-4-(1H-Imidazol-1-yl)but-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304411(CHEMBL594109 | cis-2-{4-[(1H-Imidazol-1-yl)methyl]...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304417(CHEMBL593656 | CHEMBL593877 | cis-(+/-)-4-(3,4-Dim...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304412(CHEMBL595064 | cis-4-(3,4-Dimethoxyphenyl)-2-{4-[(...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304417(CHEMBL593656 | CHEMBL593877 | cis-(+/-)-4-(3,4-Dim...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304423(CHEMBL595272 | cis-4-(3,4-Dimethoxyphenyl)-2-[4-(m...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304413(CHEMBL596447 | cis-2-[4-(1,4-Dioxa-8-azaspiro[4.5]...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304419(CHEMBL592931 | cis-4-(3,4-Dimethoxyphenyl)-2-[2-(m...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304418(CHEMBL596394 | cis-4-(3,4-Dimethoxyphenyl)-2-[3-(m...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304415(CHEMBL595038 | cis-4-(3,4-Dimethoxyphenyl)-2-{4-[(...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304422(CHEMBL605096 | cis-5-(3,4-Dimethoxyphenyl)-3-[4-(m...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304409(CHEMBL595959 | cis-2-{2-[2-(1H-Imidazol-1-yl)ethox...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304414(CHEMBL603626 | cis-4-(3,4-Dimethoxyphenyl)-2-[4-(p...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304416(CHEMBL595039 | cis-4-(3,4-Dimethoxyphenyl)-2-{4-[(...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304408(CHEMBL605935 | N-[3-(1H-Imidazol-1-yl)propyl]-2-[c...)
Affinity DataIC50:  14.3nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304421(CHEMBL603194 | cis-5-(3,4-Dimethoxyphenyl)-3-[4-(m...)
Affinity DataIC50:  16.4nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304420(6-(3,4-Dimethoxyphenyl)-2-[4-(morpholinomethyl)ben...)
Affinity DataIC50:  45.9nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304391((cis)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed