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Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50031316
TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311010(CHEMBL1078889 | N-(4-{2-[4-(1,1-Dioxo-1lambda*6*-t...)
Affinity DataIC50:  2nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311001(2-methoxy-4-(2-(4-morpholinophenylamino)pyrimidin-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311011(CHEMBL1079077 | N-(4-(2-(4-morpholinophenylamino)p...)
Affinity DataIC50:  4nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  5nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311002(CHEMBL1078275 | N-(4-(2-(3-(pyrrolidin-1-ylmethyl)...)
Affinity DataIC50:  6nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311012(CHEMBL1079078 | N-(4-(2-(4-(4-hydroxypiperidin-1-y...)
Affinity DataIC50:  6nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311004(CHEMBL1078277 | N-(4-(2-(3-(morpholinomethyl)pheny...)
Affinity DataIC50:  8nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311022(CHEMBL1078005 | N-(cyanomethyl)-4-(5-methyl-2-(4-m...)
Affinity DataIC50:  8nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311019(CHEMBL1078364 | N-(cyanomethyl)-2-methoxy-4-(2-(4-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311006(CHEMBL1078689 | N-(4-(2-(4-(morpholinomethyl)pheny...)
Affinity DataIC50:  9nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311016(2-cyano-N-(4-(2-(4-morpholinophenylamino)pyrimidin...)
Affinity DataIC50:  10nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311003(CHEMBL1078276 | N-(4-(2-(4-(piperidin-1-ylmethyl)p...)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-tagged JAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311005(CHEMBL1078688 | N-(4-(2-(3-((4-hydroxypiperidin-1-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311008(CHEMBL1078866 | N-(4-(2-(3-((4-methylpiperazin-1-y...)
Affinity DataIC50:  14nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311000(4-(4-amino-3-methoxyphenyl)-N-(4-morpholinophenyl)...)
Affinity DataIC50:  16nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311007(CHEMBL1078767 | N-(4-(2-(4-((4-hydroxypiperidin-1-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311009(CHEMBL1078971 | N-(4-(2-(4-((4-methylpiperazin-1-y...)
Affinity DataIC50:  18nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  18nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311019(CHEMBL1078364 | N-(cyanomethyl)-2-methoxy-4-(2-(4-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50310999(4-(1H-indol-5-yl)-N-(4-morpholinophenyl)pyrimidin-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  33nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311032(CHEMBL1078934 | N-(cyanomethyl)-4-(2-(4-(4-methylp...)
Affinity DataIC50:  41nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311031(CHEMBL1078933 | N-(cyanomethyl)-4-(2-(4-((4-ethylp...)
Affinity DataIC50:  47nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311030(CHEMBL1077842 | N-Cyanomethyl-4-{2-[4-(1,1-dioxo-1...)
Affinity DataIC50:  52nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311001(2-methoxy-4-(2-(4-morpholinophenylamino)pyrimidin-...)
Affinity DataIC50:  62nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311018(CHEMBL1078363 | N-(cyanomethyl)-2-methyl-4-(2-(4-m...)
Affinity DataIC50:  65nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311016(2-cyano-N-(4-(2-(4-morpholinophenylamino)pyrimidin...)
Affinity DataIC50:  66nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50310998(CHEMBL1077458 | N-(4-(2-(4-morpholinophenylamino)p...)
Affinity DataIC50:  67nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311029(CHEMBL1077841 | N-(cyanomethyl)-4-(2-(4-thiomorpho...)
Affinity DataIC50:  69nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50310997(4-(4-((2-methyl-1H-imidazol-1-yl)methyl)phenyl)-N-...)
Affinity DataIC50:  81nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50310996(4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benze...)
Affinity DataIC50:  83nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311022(CHEMBL1078005 | N-(cyanomethyl)-4-(5-methyl-2-(4-m...)
Affinity DataIC50:  85nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50310995(2,6-dimethyl-4-(2-(4-morpholinophenylamino)pyrimid...)
Affinity DataIC50:  88nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311002(CHEMBL1078275 | N-(4-(2-(3-(pyrrolidin-1-ylmethyl)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311028(CHEMBL1078229 | N-(cyanomethyl)-4-(2-(3-morpholino...)
Affinity DataIC50:  113nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311027(CHEMBL1078228 | N-(cyanomethyl)-4-(2-(3-fluoro-4-m...)
Affinity DataIC50:  116nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311015(2-(3-(2-(4-morpholinophenylamino)pyrimidin-4-yl)be...)
Affinity DataIC50:  132nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311012(CHEMBL1079078 | N-(4-(2-(4-(4-hydroxypiperidin-1-y...)
Affinity DataIC50:  149nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311031(CHEMBL1078933 | N-(cyanomethyl)-4-(2-(4-((4-ethylp...)
Affinity DataIC50:  152nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  155nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311026(CHEMBL1078721 | N-(cyanomethyl)-4-(2-(4-(morpholin...)
Affinity DataIC50:  163nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311025(CHEMBL1078720 | N-(cyanomethyl)-4-(2-(4-(3-(diethy...)
Affinity DataIC50:  166nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311023(CHEMBL1079120 | N-(cyanomethyl)-4-(5-methoxy-2-(4-...)
Affinity DataIC50:  186nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311032(CHEMBL1078934 | N-(cyanomethyl)-4-(2-(4-(4-methylp...)
Affinity DataIC50:  192nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50310994(CHEMBL1079690 | N-(furan-2-ylmethyl)-4-(2-(4-morph...)
Affinity DataIC50:  202nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311027(CHEMBL1078228 | N-(cyanomethyl)-4-(2-(3-fluoro-4-m...)
Affinity DataIC50:  274nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311021(CHEMBL1078370 | N-(cyanomethyl)-N-methyl-4-(2-(4-m...)
Affinity DataIC50:  298nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311014(2-cyano-N-(3-(2-(4-morpholinophenylamino)pyrimidin...)
Affinity DataIC50:  303nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50310993(4-(3-aminophenyl)-N-(4-morpholinophenyl)pyrimidin-...)
Affinity DataIC50:  322nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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