Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50031319
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311088BDBM50311088(cis-rac-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311084BDBM50311084((1S,2R)-1-(5-(4-chlorophenyl)thiophene-2-sulfonami...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311085BDBM50311085((1S,2R,3R)-1-(5-(4-chlorophenyl)thiophene-2-sulfon...)
Affinity DataIC50: 21nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311087BDBM50311087((1S,2R)-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2...)
Affinity DataIC50: 32nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311080BDBM50311080((1S,2R)-1-(5-(4-chlorophenyl)thiophene-2-sulfonami...)
Affinity DataIC50: 60nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28337BDBM28337((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[4-(meth...)
Affinity DataIC50: 73nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311083BDBM50311083((1S,2R)-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2...)
Affinity DataIC50: 80nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311079BDBM50311079((1S,2R)-1-(4'-chlorobiphenyl-4-ylsulfonamido)-2-ph...)
Affinity DataIC50: 84nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311081BDBM50311081((1S,2R)-1-(5-(3-chlorophenyl)thiophene-2-sulfonami...)
Affinity DataIC50: 94nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311082BDBM50311082((1S,2R)-1-(5-(5-chloropyridin-2-yl)thiophene-2-sul...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311086BDBM50311086(trans-rac-1-(5-(4-chlorophenyl)thiophene-2-sulfona...)
Affinity DataIC50: 120nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311088BDBM50311088(cis-rac-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2...)
Affinity DataIC50: 180nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311078BDBM50311078((1R,2S)-1-(4'-chlorobiphenyl-4-ylsulfonamido)-2-ph...)
Affinity DataIC50: 210nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311090BDBM50311090(rac-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2-sul...)
Affinity DataIC50: 360nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311089BDBM50311089(rac-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2-sul...)
Affinity DataIC50: 770nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311091BDBM50311091(rac-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2-sul...)
Affinity DataIC50: 800nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311088BDBM50311088(cis-rac-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed