Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50030844
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302545((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-ind...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302545((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-ind...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302545((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-ind...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228518((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302543((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of recombinant CYP3A4 using 7-benzyloxyresorufin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50133282((R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(4-meth...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228518((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302543((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228518((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302543((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant CYP3A4 using benzyloxy-4-(trifluoromethyl)coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228465(BMS-488043 | 1-(4-benzoylpiperazin-1-yl)-2-(4,7-di...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302542((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302543((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using benzyloxy-4-(trifluoromethyl)coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228518((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using 7-benzyloxyresorufin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50133282((R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(4-meth...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228518((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using 7-benzyloxyresorufin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228518((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using benzyloxy-4-(trifluoromethyl)coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50133282((R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(4-meth...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using benzyloxy-4-(trifluoromethyl)coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50133282((R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(4-meth...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50133282((R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(4-meth...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228465(BMS-488043 | 1-(4-benzoylpiperazin-1-yl)-2-(4,7-di...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228465(BMS-488043 | 1-(4-benzoylpiperazin-1-yl)-2-(4,7-di...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50133282((R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(4-meth...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using 7-benzyloxyresorufin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228465(BMS-488043 | 1-(4-benzoylpiperazin-1-yl)-2-(4,7-di...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using 7-benzyloxyresorufin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228465(BMS-488043 | 1-(4-benzoylpiperazin-1-yl)-2-(4,7-di...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using benzyloxy-4-(trifluoromethyl)coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228465(BMS-488043 | 1-(4-benzoylpiperazin-1-yl)-2-(4,7-di...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302545((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-ind...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302545((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-ind...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using 7-benzyloxyresorufin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302545((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-ind...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using benzyloxy-4-(trifluoromethyl)coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302542((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302542((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using benzyloxy-4-(trifluoromethyl)coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302542((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302542((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302543((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302543((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302542((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using 7-benzyloxyresorufin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228465(BMS-488043 | 1-(4-benzoylpiperazin-1-yl)-2-(4,7-di...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by channel flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50133282((R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(4-meth...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by channel flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302545((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-ind...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by channel flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50228518((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by channel flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by channel flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302543((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by channel flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302542((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by channel flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed