Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50030621
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099491BDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299251BDBM50299251(2-(5-chlorothiophen-2-ylthio)-2-methylpropanoic ac...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299253BDBM50299253((S)-2-(5-methoxybenzo[d]thiazol-2-ylthio)propanoic...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299252BDBM50299252(2-[(5-Bromo-1,3-benzothiazol-2-yl)thio]-2-methylpr...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299255BDBM50299255(rac-2-[(5-Chloro-1,3-benzothiazol-2-yl)thio]pentan...)
Affinity DataEC50:  9.30E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299254BDBM50299254(rac-2-[(5-Bromo-1,3-benzothiazol-2-yl)thio]propano...)
Affinity DataEC50:  9.30E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299258BDBM50299258(rac-2-[(6-Ethoxy-1,3-benzothiazol-2-yl)thio]propan...)
Affinity DataEC50:  9.80E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299257BDBM50299257(rac-[(5-Chloro-1,3-benzothiazol-2-yl)thio](phenyl)...)
Affinity DataEC50:  1.43E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299256BDBM50299256(rac-2-[(6-Ethoxy-1,3-benzothiazol-2-yl)thio]pentan...)
Affinity DataEC50:  1.48E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299253BDBM50299253((S)-2-(5-methoxybenzo[d]thiazol-2-ylthio)propanoic...)
Affinity DataEC50:  3.33E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299260BDBM50299260(2-(5-chlorobenzo[d]thiazol-2-ylthio)-2-methylpropa...)
Affinity DataEC50:  3.59E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299261BDBM50299261(2-[(6-Trifluoromethyl-1,3-benzothiazol-2-yl)thio]-...)
Affinity DataEC50:  3.61E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299259BDBM50299259(2-[(6-Chloro-1,3-benzothiazol-2-yl)thio]-2-methylp...)
Affinity DataEC50:  3.89E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299264BDBM50299264(2-[(6-Bromo-1,3-benzothiazol-2-yl)thio]-2-methylpr...)
Affinity DataEC50:  4.58E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299263BDBM50299263(2-[(5-Methoxy-1,3-benzothiazol-2-yl)thio]-2-methyl...)
Affinity DataEC50:  4.58E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299262BDBM50299262(2-[(5-Cyano-1,3-benzothiazol-2-yl)thio]-2-methylpr...)
Affinity DataEC50:  4.63E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28699BDBM28699(2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMB...)
Affinity DataEC50:  5.50E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299266BDBM50299266((S)-2-(5-chlorobenzo[d]thiazol-2-ylthio)propanoic ...)
Affinity DataEC50:  5.59E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299265BDBM50299265((R)-2-(5-methoxybenzo[d]thiazol-2-ylthio)propanoic...)
Affinity DataEC50:  5.73E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299266BDBM50299266((S)-2-(5-chlorobenzo[d]thiazol-2-ylthio)propanoic ...)
Affinity DataEC50:  6.25E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299267BDBM50299267(2-[(6-Ethoxy-1,3-benzothiazol-2-yl)thio]-2-methylp...)
Affinity DataEC50:  6.93E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299269BDBM50299269((R)-2-(5-chlorobenzo[d]thiazol-2-ylthio)propanoic ...)
Affinity DataEC50:  7.35E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299268BDBM50299268(rac-2-[(6-Bromo-1,3-benzothiazol-2-yl)thio]propano...)
Affinity DataEC50:  8.43E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as receptor transactivation at by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed