Compile Data Set for Download or QSAR
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Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50030628
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299378(CHEMBL575340 | N4-(2,3-dihydro-1H-inden-2-yl)-2-(p...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299360(CHEMBL575741 | N2-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299374((R)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(3-methylpipe...)
Affinity DataIC50:  8nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299366(4-(2,3-dihydro-1H-inden-2-yloxy)-6-(piperazin-1-yl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299372(6-(1,4-diazepan-1-yl)-N2-(2,3-dihydro-1H-inden-2-y...)
Affinity DataIC50:  11nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299378(CHEMBL575340 | N4-(2,3-dihydro-1H-inden-2-yl)-2-(p...)
Affinity DataIC50:  12nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299379(CHEMBL578643 | N4-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  14nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299372(6-(1,4-diazepan-1-yl)-N2-(2,3-dihydro-1H-inden-2-y...)
Affinity DataIC50:  17nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299364(6-(piperazin-1-yl)-N2-(pyridin-4-yl)-N4-(1,2,3,4-t...)
Affinity DataIC50:  23nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299374((R)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(3-methylpipe...)
Affinity DataIC50:  26nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299360(CHEMBL575741 | N2-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299366(4-(2,3-dihydro-1H-inden-2-yloxy)-6-(piperazin-1-yl...)
Affinity DataIC50:  57nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299373(CHEMBL577177 | N2-(2,3-dihydro-1H-inden-2-yl)-N4-m...)
Affinity DataIC50:  81nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299377((S)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(2-methylpipe...)
Affinity DataIC50:  87nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299376((R)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(2-methylpipe...)
Affinity DataIC50:  118nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299375((S)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(3-methylpipe...)
Affinity DataIC50:  135nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299379(CHEMBL578643 | N4-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  154nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299365(CHEMBL567603 | N2-(2,3-dihydro-1H-inden-1-yl)-6-(p...)
Affinity DataIC50:  185nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299371(CHEMBL573152 | N2-(2,3-dihydro-1H-inden-2-yl)-6-(4...)
Affinity DataIC50:  305nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299362(CHEMBL575798 | N2-phenethyl-6-(piperazin-1-yl)-N4-...)
Affinity DataIC50:  326nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299363(CHEMBL575555 | N2-benzyl-6-(piperazin-1-yl)-N4-(py...)
Affinity DataIC50:  400nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299361(CHEMBL575962 | N2-cyclopentyl-6-(piperazin-1-yl)-N...)
Affinity DataIC50:  890nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299368(CHEMBL575973 | N2-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299380(CHEMBL572911 | N2-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299369(CHEMBL575974 | N2-(2,3-dihydro-1H-inden-2-yl)-N4-p...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299370(CHEMBL573151 | N2-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299367(CHEMBL575761 | N2-(2,3-dihydro-1H-inden-2-yl)-6-(p...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed