Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50038935
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299487BDBM50299487({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299488BDBM50299488({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299489BDBM50299489({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299489BDBM50299489({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299490BDBM50299490({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299487BDBM50299487({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299491BDBM50299491([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299488BDBM50299488({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299492BDBM50299492({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299491BDBM50299491([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299493BDBM50299493({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299494BDBM50299494({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299492BDBM50299492({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299495BDBM50299495({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299490BDBM50299490({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299496BDBM50299496({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299493BDBM50299493({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299494BDBM50299494({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299497BDBM50299497({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299497BDBM50299497({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299496BDBM50299496({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299495BDBM50299495({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299498BDBM50299498({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 77nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299498BDBM50299498({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant HER4 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4 in pooled human liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333373BDBM50333373([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed