Compile Data Set for Download or QSAR
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Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50031367
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312070(CHEMBL1080438 | N-(3-(3-(1H-pyrazol-4-yl)pyrazolo[...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312058(CHEMBL1087522 | N-(3-(3-(4-(pyrrolidin-1-ylmethyl)...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50:  25nMAssay Description:Inhibition of cRAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312054(CHEMBL1087892 | N-(3-(3-(4-(2-(dimethylamino)ethyl...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312062(CHEMBL1087781 | N-(3-(3-(6-(2-(dimethylamino)ethyl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312073(CHEMBL1076204 | N-(4-fluoro-3-(3-(6-(4-methylpiper...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312050(CHEMBL1076440 | N-(3-(3-(4-(2-(dimethylamino)aceta...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312059(CHEMBL1076482 | N-(3-(3-(4-((4-methylpiperazin-1-y...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312051(CHEMBL1076441 | N-(3-(3-(3-(2-(dimethylamino)aceta...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312053(CHEMBL1088295 | N-(3-(3-(3-(2-(dimethylamino)ethyl...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312071(CHEMBL1080439 | N-(3-(3-(1H-pyrazol-4-yl)pyrazolo[...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312056(CHEMBL1087894 | N-(3-(3-(3-((dimethylamino)methyl)...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312063(CHEMBL1076497 | N-(3-(3-(6-(4-methylpiperazin-1-yl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312048(CHEMBL1086870 | N-(3-(3-(3-carbamoylphenyl)pyrazol...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312065(CHEMBL1081470 | N-(3-(3-(1H-pyrazol-4-yl)pyrazolo[...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312072(CHEMBL1080437 | N-(3-(3-(1H-pyrazol-4-yl)pyrazolo[...)
Affinity DataIC50:  98nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312061(CHEMBL1087780 | N-(3-(3-(6-aminopyridin-3-yl)pyraz...)
Affinity DataIC50:  112nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312060(CHEMBL1087523 | N-(3-(3-(pyridin-3-yl)pyrazolo[1,5...)
Affinity DataIC50:  113nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312055(CHEMBL1087893 | N-(3-(3-(2-((dimethylamino)methyl)...)
Affinity DataIC50:  117nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312049(CHEMBL1076439 | N-(3-(3-(4-(2-(2-methoxyethoxy)ace...)
Affinity DataIC50:  139nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50:  216nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312069(CHEMBL1076541 | N-(3-(3-(5-((4-ethylpiperazin-1-yl...)
Affinity DataIC50:  219nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312046(CHEMBL1080269 | N-(3-(3-(4-(dimethylamino)phenyl)p...)
Affinity DataIC50:  308nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312052(CHEMBL1088162 | N-(3-(3-(2-(2-(dimethylamino)ethyl...)
Affinity DataIC50:  318nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312067(CHEMBL1081817 | N-(3-(3-(furan-3-yl)pyrazolo[1,5-a...)
Affinity DataIC50:  326nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312068(CHEMBL1081818 | N-(3-(3-(5-(pyrrolidin-1-ylmethyl)...)
Affinity DataIC50:  362nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312066(CHEMBL1081647 | N-(3-(3-(1-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50:  393nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312044(CHEMBL1080656 | N-(3-(3-(5-morpholinopent-1-ynyl)p...)
Affinity DataIC50:  552nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312045(CHEMBL1080268 | N-(3-(3-(5-(4-methylpiperazin-1-yl...)
Affinity DataIC50:  842nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312064(CHEMBL1087906 | N-(3-(3-(2-morpholinopyrimidin-5-y...)
Affinity DataIC50:  941nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50294451(CHEMBL565061 | ethyl 7-(3-(3-(trifluoromethyl)benz...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of IKKbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMAP kinase-activated protein kinase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of MKK6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PLK1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C alpha type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312057(CHEMBL1087397 | N-(3-(3-(4-((dimethylamino)methyl)...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312047(CHEMBL1080445 | N-(3-(3-(4-(N,N-dimethylsulfamoyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed