Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 50031368
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133817BDBM50133817(BCTC | CHEMBL441472 | N-(4-tert-butylphenyl)-4-(3-...)
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312085BDBM50312085(4-tert-butylphenyl 4-(3-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312091BDBM50312091(biphenyl-3-yl 4-(3-(trifluoromethyl)pyridin-2-yl)p...)
Affinity DataIC50: 380nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312078BDBM50312078(4-tert-butylphenyl 4-(3-chloropyridin-2-yl)piperaz...)
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26741BDBM26741(N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carbo...)
Affinity DataIC50: 500nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312082BDBM50312082(4-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-...)
Affinity DataEC50:  600nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312088BDBM50312088(3-(trifluoromethyl)phenyl 4-(3-(trifluoromethyl)py...)
Affinity DataIC50: 610nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312090BDBM50312090(3-chlorophenyl 4-(3-(trifluoromethyl)pyridin-2-yl)...)
Affinity DataIC50: 740nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312084BDBM50312084(biphenyl-3-yl 4-(3-chloropyridin-2-yl)piperazine-1...)
Affinity DataIC50: 750nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312086BDBM50312086(3-tert-butylphenyl 4-(3-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 770nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312083BDBM50312083(3-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-...)
Affinity DataIC50: 910nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312087BDBM50312087(4-(trifluoromethyl)phenyl 4-(3-(trifluoromethyl)py...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312091BDBM50312091(biphenyl-3-yl 4-(3-(trifluoromethyl)pyridin-2-yl)p...)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312083BDBM50312083(3-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312079BDBM50312079(1-(4-(3-(3-tert-butylphenyl)prop-1-en-2-yl)cyclohe...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312078BDBM50312078(4-tert-butylphenyl 4-(3-chloropyridin-2-yl)piperaz...)
Affinity DataEC50:  1.60E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312079BDBM50312079(1-(4-(3-(3-tert-butylphenyl)prop-1-en-2-yl)cyclohe...)
Affinity DataEC50:  1.80E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312081BDBM50312081(3-(trifluoromethyl)phenyl 4-(3-chloropyridin-2-yl)...)
Affinity DataEC50:  2.00E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312089BDBM50312089(4-chlorophenyl 4-(3-(trifluoromethyl)pyridin-2-yl)...)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312092BDBM50312092(4-(trifluoromethyl)phenyl 4-(pyridin-2-ylmethyl)pi...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312080BDBM50312080(4-(trifluoromethyl)phenyl 4-(3-chloropyridin-2-yl)...)
Affinity DataEC50:  3.10E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312087BDBM50312087(4-(trifluoromethyl)phenyl 4-(3-(trifluoromethyl)py...)
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312090BDBM50312090(3-chlorophenyl 4-(3-(trifluoromethyl)pyridin-2-yl)...)
Affinity DataEC50:  3.70E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312081BDBM50312081(3-(trifluoromethyl)phenyl 4-(3-chloropyridin-2-yl)...)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312080BDBM50312080(4-(trifluoromethyl)phenyl 4-(3-chloropyridin-2-yl)...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312074BDBM50312074(4-chlorophenyl 4-(pyridin-2-ylmethyl)piperazine-1-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133817BDBM50133817(BCTC | CHEMBL441472 | N-(4-tert-butylphenyl)-4-(3-...)
Affinity DataEC50:  4.50E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312089BDBM50312089(4-chlorophenyl 4-(3-(trifluoromethyl)pyridin-2-yl)...)
Affinity DataIC50: 4.60E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312075BDBM50312075(4-chlorophenyl 4-(quinolin-2-ylmethyl)piperazine-1...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312082BDBM50312082(4-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-...)
Affinity DataIC50: 6.44E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312081BDBM50312081(3-(trifluoromethyl)phenyl 4-(3-chloropyridin-2-yl)...)
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312093BDBM50312093(4-(trifluoromethyl)phenyl 4-(quinolin-2-ylmethyl)p...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]AEA in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312074BDBM50312074(4-chlorophenyl 4-(pyridin-2-ylmethyl)piperazine-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312080BDBM50312080(4-(trifluoromethyl)phenyl 4-(3-chloropyridin-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312079BDBM50312079(1-(4-(3-(3-tert-butylphenyl)prop-1-en-2-yl)cyclohe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312083BDBM50312083(3-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312075BDBM50312075(4-chlorophenyl 4-(quinolin-2-ylmethyl)piperazine-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312082BDBM50312082(4-chlorophenyl 4-(3-chloropyridin-2-yl)piperazine-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312094BDBM50312094(N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-4-(pyridin-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312092BDBM50312092(4-(trifluoromethyl)phenyl 4-(pyridin-2-ylmethyl)pi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312077BDBM50312077(N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-4-(3-(trifluo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312093BDBM50312093(4-(trifluoromethyl)phenyl 4-(quinolin-2-ylmethyl)p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312095BDBM50312095(N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-4-(quinolin-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312091BDBM50312091(biphenyl-3-yl 4-(3-(trifluoromethyl)pyridin-2-yl)p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312086BDBM50312086(3-tert-butylphenyl 4-(3-(trifluoromethyl)pyridin-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312090BDBM50312090(3-chlorophenyl 4-(3-(trifluoromethyl)pyridin-2-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312084BDBM50312084(biphenyl-3-yl 4-(3-chloropyridin-2-yl)piperazine-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26741BDBM26741(N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carbo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312088BDBM50312088(3-(trifluoromethyl)phenyl 4-(3-(trifluoromethyl)py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312076BDBM50312076(4-(3-chloropyridin-2-yl)-N-(2-(5-hydroxy-1H-indol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
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