Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50030870
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303103BDBM50303103(1-(3-(3-(4-chloro-3-hydroxyphenyl)-2-(pyridin-4-yl...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303121BDBM50303121(ethyl 3-(3-(7-chloro-1H-indazol-4-yl)-2-(pyridin-4...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303123BDBM50303123(ethyl 3-(3-(7-fluoro-1H-indazol-4-yl)-2-(pyridin-4...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303098BDBM50303098(5-(7-(8-azabicyclo[3.2.1]octan-3-yl)-2-(pyridin-4-...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303100BDBM50303100(2-chloro-5-(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303131BDBM50303131(2-chloro-5-[13-(hydroxymethyl)-15-methyl-5-(pyridi...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303127BDBM50303127(ethyl 3-(3-(7-methyl-1H-indazol-4-yl)-2-(pyridin-4...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303132BDBM50303132(2-chloro-5-[13-(hydroxymethyl)-15-methyl-5-(pyridi...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303094BDBM50303094(ethyl 3-(3-(3-hydroxyphenyl)-2-(pyridin-4-yl)-1,2-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303130BDBM50303130(Methyl 6-(4-chloro-3-hydroxyphenyl)-15-methyl-5-(p...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303110BDBM50303110(ethyl 3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303111BDBM50303111((2R)-1-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyr...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303102BDBM50303102(5-(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-2-(py...)
Affinity DataIC50: 3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303124BDBM50303124(7-(8-azabicyclo[3.2.1]octan-3-yl)-3-(7-fluoro-1H-i...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303097BDBM50303097(3-(7-(8-azabicyclo[3.2.1]octan-3-yl)-2-(pyridin-4-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303125BDBM50303125(ethyl 3-(2-(pyridin-4-yl)-3-(7-(trifluoromethyl)-1...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303122BDBM50303122(3-(7-chloro-1H-indazol-4-yl)-7-(8-ethyl-8-azabicyc...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303112BDBM50303112(3-(1H-indazol-4-yl)-7-(8-(methylsulfonyl)-8-azabic...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303113BDBM50303113(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dihydr...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303114BDBM50303114(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dihydr...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303129BDBM50303129(ethyl 3-(3-(1H-indazol-4-yl)-6-methyl-2-(pyridin-4...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303096BDBM50303096(7-(8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chloro-3-me...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303115BDBM50303115(1-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dih...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303128BDBM50303128(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-3-(7-met...)
Affinity DataIC50: 17nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303116BDBM50303116(2-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dih...)
Affinity DataIC50: 22.8nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303106BDBM50303106(ethyl 3-(3-(1H-indol-6-yl)-2-(pyridin-4-yl)-1,2-di...)
Affinity DataIC50: 36nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303117BDBM50303117((2R)-tert-butyl 1-(3-(3-(1H-indazol-4-yl)-2-(pyrid...)
Affinity DataIC50: 39.4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303099BDBM50303099(3-(4-chloro-3-methoxyphenyl)-7-(8-ethyl-8-azabicyc...)
Affinity DataIC50: 43.5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303126BDBM50303126(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-2-(pyrid...)
Affinity DataIC50: 45nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303118BDBM50303118(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-3-(1H-in...)
Affinity DataIC50: 46.6nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303093BDBM50303093(ethyl 3-(3-(4-chloro-3-methoxyphenyl)-2-(pyridin-4...)
Affinity DataIC50: 54.1nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303101BDBM50303101(4-(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-2-(py...)
Affinity DataIC50: 57.9nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303119BDBM50303119(3-(1H-indazol-4-yl)-7-(8-isopropyl-8-azabicyclo[3....)
Affinity DataIC50: 67nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303095BDBM50303095(7-(8-azabicyclo[3.2.1]octan-3-yl)-3-(3-methoxyphen...)
Affinity DataIC50: 70.8nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303120BDBM50303120(1-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dih...)
Affinity DataIC50: 75.9nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303092BDBM50303092(ethyl 3-(3-(3-methoxyphenyl)-2-(pyridin-4-yl)-1,2-...)
Affinity DataIC50: 87nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303105BDBM50303105(ethyl 3-(3-(4-(1,3,4-oxadiazol-2-yl)phenyl)-2-(pyr...)
Affinity DataIC50: 151nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303104BDBM50303104(ethyl 3-(3-(3,4-difluorophenyl)-2-(pyridin-4-yl)-1...)
Affinity DataIC50: 302nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303109BDBM50303109(ethyl 3-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303108BDBM50303108(ethyl 3-(3-(2-oxoindolin-6-yl)-2-(pyridin-4-yl)-1,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50303107BDBM50303107(ethyl 3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)-1,2-di...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed