Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50031369
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312096BDBM50312096(N-(3-(3-chlorobenzamido)phenyl)-2-methoxybenzamide...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312148BDBM50312148(3-(1,3-dioxoisoindolin-2-yl)-N-(2-hydroxyphenyl)be...)
Affinity DataIC50: 77nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312149BDBM50312149(N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-5-...)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312096BDBM50312096(N-(3-(3-chlorobenzamido)phenyl)-2-methoxybenzamide...)
Affinity DataKi:  301nMAssay Description:Displacement of [3H]3-methoxy-5-(2-pyridinylethynyl) pyridine from mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312096BDBM50312096(N-(3-(3-chlorobenzamido)phenyl)-2-methoxybenzamide...)
Affinity DataIC50: 880nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312144BDBM50312144(3-(1,3-dioxoisoindolin-2-yl)-N-(2-fluorophenyl)ben...)
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312143BDBM50312143(3-(1,3-dioxoisoindolin-2-yl)-N-(pyridin-2-yl)benza...)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312105BDBM50312105(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Affinity DataIC50: 1.35E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312141BDBM50312141(N-(2-chlorophenyl)-3-(1,3-dioxoisoindolin-2-yl)ben...)
Affinity DataIC50: 1.78E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312104BDBM50312104(N-(3-(3-cyanobenzamido)phenyl)-2-methoxybenzamide ...)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312134BDBM50312134(3-chloro-N-(3-(cyclopropanecarboxamido)phenyl)benz...)
Affinity DataIC50: 2.23E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312118BDBM50312118(2-chloro-N-(3-(3-chlorobenzamido)phenyl)benzamide ...)
Affinity DataIC50: 2.62E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312139BDBM50312139(N-(3,5-dimethoxyphenyl)-3-(1,3-dioxoisoindolin-2-y...)
Affinity DataIC50: 3.58E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312127BDBM50312127(N-(3-(3-chlorobenzamido)phenyl)furan-2-carboxamide...)
Affinity DataIC50: 4.51E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312133BDBM50312133(3-chloro-N-(3-(cyclobutanecarboxamido)phenyl)benza...)
Affinity DataIC50: 5.27E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312135BDBM50312135(3-chloro-N-(3-isobutyramidophenyl)benzamide | CHEM...)
Affinity DataIC50: 5.82E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312101BDBM50312101(N-(3-(3-fluorobenzamido)phenyl)-2-methoxybenzamide...)
Affinity DataIC50: 6.48E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312138BDBM50312138(3-(1,3-dioxoisoindolin-2-yl)-N-(3-hydroxyphenyl)be...)
Affinity DataIC50: 7.79E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312136BDBM50312136(N-(3-acetamidophenyl)-3-chlorobenzamide | CHEMBL10...)
Affinity DataIC50: 7.97E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312103BDBM50312103(2-methoxy-N-(3-(3-(trifluoromethyl)benzamido)pheny...)
Affinity DataIC50: 1.06E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312115BDBM50312115(N-(3-isobutyramidophenyl)-2-methoxybenzamide | CHE...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312114BDBM50312114(N-(3-(cyclopropanecarboxamido)phenyl)-2-methoxyben...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312113BDBM50312113(N-(3-(cyclobutanecarboxamido)phenyl)-2-methoxybenz...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312112BDBM50312112(N-(3-(cyclopentanecarboxamido)phenyl)-2-methoxyben...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312119BDBM50312119(N,N'-(1,3-phenylene)bis(3-chlorobenzamide) | CHEMB...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312117BDBM50312117(2-methoxy-N-(3-(2-methoxyacetamido)phenyl)benzamid...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312116BDBM50312116(N-(3-acetamidophenyl)-2-methoxybenzamide | CHEMBL1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312123BDBM50312123(3-chloro-N-(3-(4-fluorobenzamido)phenyl)benzamide ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312122BDBM50312122(3-chloro-N-(3-(3-fluorobenzamido)phenyl)benzamide ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312121BDBM50312121(3,4-dichloro-N-(3-(3-chlorobenzamido)phenyl)benzam...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312120BDBM50312120(3-chloro-N-(3-(4-chlorobenzamido)phenyl)benzamide ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312126BDBM50312126(N-(3-(3-chlorobenzamido)phenyl)benzo[d][1,3]dioxol...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312125BDBM50312125(3-chloro-N-(3-(3-methylbenzamido)phenyl)benzamide ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312124BDBM50312124(3-chloro-N-(3-(3-(trifluoromethyl)benzamido)phenyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312131BDBM50312131(3-chloro-N-(3-(cyclohexanecarboxamido)phenyl)benza...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312130BDBM50312130(Adamantane-1-carboxylic acid [3-(3-chloro-benzoyla...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312129BDBM50312129(3-chloro-N-(3-(2-phenylcyclopropanecarboxamido)phe...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312128BDBM50312128(3-chloro-N-(3-(2-phenylacetamido)phenyl)benzamide ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312132BDBM50312132(3-chloro-N-(3-(cyclopentanecarboxamido)phenyl)benz...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312137BDBM50312137(3-chloro-N-(3-(2-methoxyacetamido)phenyl)benzamide...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312142BDBM50312142(3-(1,3-dioxoisoindolin-2-yl)-N-(pyridin-3-yl)benza...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312140BDBM50312140(3-(1,3-dioxoisoindolin-2-yl)-N-(2-methoxyphenyl)be...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312147BDBM50312147(N-(bicyclo[2.2.1]heptan-2-yl)-3-(1,3-dioxoisoindol...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312146BDBM50312146(N-cyclopropyl-3-(1,3-dioxoisoindolin-2-yl)benzamid...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312145BDBM50312145(cid_1255868 | CHEMBL1081043 | 3-(1,3-dioxoisoindol...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312099BDBM50312099(3,4-dichloro-N-(3-(2-methoxybenzamido)phenyl)benza...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312098BDBM50312098(N-(3-(4-chlorobenzamido)phenyl)-2-methoxybenzamide...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312097BDBM50312097(2-chloro-N-(3-(2-methoxybenzamido)phenyl)benzamide...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312102BDBM50312102(N-(3-(4-fluorobenzamido)phenyl)-2-methoxybenzamide...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312100BDBM50312100(3,5-dichloro-N-(3-(2-methoxybenzamido)phenyl)benza...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
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