Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50004284
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481154BDBM50481154(CHEMBL570980)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481148BDBM50481148(CHEMBL570752)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481164BDBM50481164(CHEMBL585911)
Affinity DataIC50: 1nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481147BDBM50481147(CHEMBL585542)
Affinity DataIC50: 1nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481161BDBM50481161(CHEMBL571429)
Affinity DataIC50: 2nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481163BDBM50481163(CHEMBL568933)
Affinity DataIC50: 2nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481149BDBM50481149(CHEMBL582818)
Affinity DataIC50: 4nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481153BDBM50481153(CHEMBL571663)
Affinity DataIC50: 8nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481165BDBM50481165(CHEMBL583663)
Affinity DataIC50: 9nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481150BDBM50481150(CHEMBL571186)
Affinity DataIC50: 13nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481150BDBM50481150(CHEMBL571186)
Affinity DataIC50: 13nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481162BDBM50481162(CHEMBL582822)
Affinity DataIC50: 20nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481146BDBM50481146(CHEMBL571401)
Affinity DataIC50: 26nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481156BDBM50481156(CHEMBL570062)
Affinity DataIC50: 26nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481144BDBM50481144(CHEMBL585913)
Affinity DataIC50: 66nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481138BDBM50481138(CHEMBL572074)
Affinity DataIC50: 70nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481158BDBM50481158(CHEMBL571246)
Affinity DataIC50: 175nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481151BDBM50481151(CHEMBL571428)
Affinity DataIC50: 194nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481159BDBM50481159(CHEMBL584118)
Affinity DataIC50: 202nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481152BDBM50481152(CHEMBL585544)
Affinity DataIC50: 678nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481141BDBM50481141(CHEMBL571883)
Affinity DataIC50: 826nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481143BDBM50481143(CHEMBL571188)
Affinity DataIC50: 989nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481142BDBM50481142(CHEMBL571665)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481166BDBM50481166(CHEMBL571664)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481139BDBM50481139(CHEMBL570862)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481157BDBM50481157(CHEMBL572263)
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481140BDBM50481140(CHEMBL571853)
Affinity DataIC50: 5.65E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481145BDBM50481145(CHEMBL570755)
Affinity DataIC50: 5.72E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481150BDBM50481150(CHEMBL571186)
Affinity DataIC50: 5.95E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481138BDBM50481138(CHEMBL572074)
Affinity DataIC50: 6.27E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481138BDBM50481138(CHEMBL572074)
Affinity DataIC50: 6.28E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481160BDBM50481160(CHEMBL570974)
Affinity DataIC50: 6.44E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481155BDBM50481155(CHEMBL572075)
Affinity DataIC50: 8.81E+3nMAssay Description:Inhibition of gamma secretase in human IMR32 cells assessed as inhibition of Abeta40 site cleavage by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed