Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 3509
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35751BDBM35751(cis-1,2-diaminocyclohexane derivative, 8h)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35756BDBM35756(cis-1,2-diaminocyclohexane derivative, 8m)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35743BDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35759BDBM35759(cis-1,2-diaminocyclohexane derivative, 8p)
Affinity DataIC50: 3.20nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35753BDBM35753(cis-1,2-diaminocyclohexane derivative, 8j)
Affinity DataIC50: 3.5nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35754BDBM35754(cis-1,2-diaminocyclohexane derivative, 8k)
Affinity DataIC50: 4.80nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35755BDBM35755(cis-1,2-diaminocyclohexane derivative, 8l)
Affinity DataIC50: 5.70nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35748BDBM35748(cis-1,2-diaminocyclohexane derivative, 8e)
Affinity DataIC50: 6.5nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35758BDBM35758(cis-1,2-diaminocyclohexane derivative, 8o)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35757BDBM35757(cis-1,2-diaminocyclohexane derivative, 8n)
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35752BDBM35752(cis-1,2-diaminocyclohexane derivative, 8i)
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35750BDBM35750(cis-1,2-diaminocyclohexane derivative, 8g)
Affinity DataIC50: 55nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35749BDBM35749(cis-1,2-diaminocyclohexane derivative, 8f)
Affinity DataIC50: 69nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35744BDBM35744(cis-1,2-diaminocyclohexane derivative, 8a)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35745BDBM35745(cis-1,2-diaminocyclohexane derivative, 8b)
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35746BDBM35746(cis-1,2-diaminocyclohexane derivative, 8c)
Affinity DataIC50: 1.90E+3nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandChemical structure of BindingDB Monomer ID 35747BDBM35747(cis-1,2-diaminocyclohexane derivative, 8d)
Affinity DataIC50: 2.30E+3nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2009
Entry Details Article
PubMed