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Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 3477
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35298(benzoylguanidine, 18)
Affinity DataIC50:  2nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35303(isonicotinoyl guanidine, 23)
Affinity DataIC50:  3nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35299(benzoylguanidine, 19)
Affinity DataIC50:  3nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35300(benzoylguanidine, 20)
Affinity DataIC50:  3nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35313(nicotinoyl guanidine, 33)
Affinity DataIC50:  3.30nMT: 25°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35302(nicotinoyl guanidine, 22)
Affinity DataIC50:  4nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35305(heteroaroylguanidine, 25)
Affinity DataIC50:  4nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35311(nicotinoyl guanidine, 31)
Affinity DataIC50:  4nMT: 25°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35294(benzoylguanidine, 14)
Affinity DataIC50:  5nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35312(nicotinoyl guanidine, 32)
Affinity DataIC50:  5nMT: 25°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35315(nicotinoyl guanidine, 35)
Affinity DataIC50:  6nMT: 25°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35306(heteroaroylguanidine, 26)
Affinity DataIC50:  6nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35297(benzoylguanidine, 17)
Affinity DataIC50:  6nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35292(benzoylguanidine, 12)
Affinity DataIC50:  6nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35293(benzoylguanidine, 13)
Affinity DataIC50:  7nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35307(heteroaroylguanidine, 27)
Affinity DataIC50:  9nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35316(BMS-344577)
Affinity DataIC50:  9nMT: 25°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35296(benzoylguanidine, 16)
Affinity DataIC50:  10nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35309(nicotinoyl guanidine, 29)
Affinity DataIC50:  10nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35285(sulfonylguanidine, 5)
Affinity DataIC50:  10nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35286(sulfamoylguanidine, 6)
Affinity DataIC50:  12nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35314(nicotinoyl guanidine, 34)
Affinity DataIC50:  12nMT: 25°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35283(CHEMBL551991 | cyanoguanidine, 3)
Affinity DataIC50:  12nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35291(carbamoylguanidine, 11)
Affinity DataIC50:  15nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35310(nicotinoyl guanidine, 30)
Affinity DataIC50:  17nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35288(acetylguanidine, 8)
Affinity DataIC50:  17nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35295(benzoylguanidine, 15)
Affinity DataIC50:  18nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35287(sulfonylguanidine, 7)
Affinity DataIC50:  24nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35284(nitroguanidine, 4)
Affinity DataIC50:  25nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35290(carbamoylguanidine, 10)
Affinity DataIC50:  28nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM26351(2-methylbenzofuran compound, 2 | 2-{[(2-methyl-1-b...)
Affinity DataIC50:  30nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35289(ethoxylcarbonylguanidine, 9)
Affinity DataIC50:  32nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35304(heteroaroylguanidine, 24)
Affinity DataIC50:  50nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35301(picolinoyl guanidine, 21)
Affinity DataIC50:  55nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM35308(tetrazoloyl guanidine, 28)
Affinity DataIC50:  56nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM26350((S)-1-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)aze...)
Affinity DataIC50:  110nMpH: 7.4 T: 22°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed