Compile Data Set for Download or QSAR
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Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 3510
TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35767(cis-1,2-diaminocyclohexane derivative, 5h)
Affinity DataIC50:  0.430nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35769(cis-1,2-diaminocyclohexane derivative, 5j)
Affinity DataIC50:  1.40nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataIC50:  2.30nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35762(cis-1,2-diaminocyclohexane derivative, 5c)
Affinity DataIC50:  3nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35765(cis-1,2-diaminocyclohexane derivative, 5f)
Affinity DataIC50:  3.30nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35773(cis-1,2-diaminocyclohexane derivative, 48)
Affinity DataIC50:  3.40nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35763(cis-1,2-diaminocyclohexane derivative, 5d)
Affinity DataIC50:  4.10nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35770(cis-1,2-diaminocyclohexane derivative, 5k)
Affinity DataIC50:  4.90nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35760(cis-1,2-diaminocyclohexane derivative, 5a)
Affinity DataIC50:  5.70nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35772(cis-1,2-diaminocyclohexane derivative, 45c)
Affinity DataIC50:  9.5nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35771(cis-1,2-diaminocyclohexane derivative, 45a)
Affinity DataIC50:  12nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35768(cis-1,2-diaminocyclohexane derivative, 5i)
Affinity DataIC50:  12nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35766(cis-1,2-diaminocyclohexane derivative, 5g)
Affinity DataIC50:  35nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35764(cis-1,2-diaminocyclohexane derivative, 5e)
Affinity DataIC50:  870nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Daiichi Sankyo

LigandPNGBDBM35761(cis-1,2-diaminocyclohexane derivative, 5b)
Affinity DataIC50:  4.00E+3nMpH: 7.4 T: 23°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed