Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50000904
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011032(CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011032(CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011032(CHEMBL333687 | Atorvastatin lactone | 5-(4-Fluoro-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011018(CHEMBL332165 | 6-{2-[3,4-Dichloro-2-(4-fluoro-phen...)
Affinity DataIC50: 28nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011020(CHEMBL121658 | 6-{2-[3,4-Dibromo-2-(4-fluoro-pheny...)
Affinity DataIC50: 28nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011036(2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50: 30nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011035(CHEMBL331453 | 5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy...)
Affinity DataIC50: 40nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011025(CHEMBL330753 | 6-{2-[2-(4-Fluoro-phenyl)-5-isoprop...)
Affinity DataIC50: 46nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011024(CHEMBL122219 | 2-(4-Fluoro-phenyl)-1-[2-(4-hydroxy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011029(CHEMBL120949 | 6-{2-[2-(4-Fluoro-phenyl)-5-isoprop...)
Affinity DataIC50: 71nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011021(CHEMBL333361 | 6-{2-[5-(4-Fluoro-phenyl)-2-isoprop...)
Affinity DataIC50: 120nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011033(CHEMBL331952 | 6-{2-[2-(4-Fluoro-phenyl)-5-isoprop...)
Affinity DataIC50: 140nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011022(CHEMBL330777 | 1-[2-(4-Hydroxy-6-oxo-tetrahydro-py...)
Affinity DataIC50: 170nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011023(CHEMBL123357 | 2-(4-Fluoro-phenyl)-1-[2-(4-hydroxy...)
Affinity DataIC50: 180nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011028(CHEMBL420354 | 5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy...)
Affinity DataIC50: 200nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011034(CHEMBL104044 | 6-{2-[2-(4-Fluoro-phenyl)-5-isoprop...)
Affinity DataIC50: 230nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011016(CHEMBL331411 | 4-(4-Cyano-phenyl)-5-(4-fluoro-phen...)
Affinity DataIC50: 280nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011017(CHEMBL120897 | 6-{2-[2-(4-Fluoro-phenyl)-5-isoprop...)
Affinity DataIC50: 310nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011019(CHEMBL333478 | 6-{2-[2-(4-Fluoro-phenyl)-5-isoprop...)
Affinity DataIC50: 347nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011026(CHEMBL123986 | 2-(4-Fluoro-phenyl)-1-[2-(4-hydroxy...)
Affinity DataIC50: 350nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011031(CHEMBL333206 | 6-{2-[2-(4-Fluoro-phenyl)-5-isoprop...)
Affinity DataIC50: 800nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011027(CHEMBL420337 | 2-Ethyl-1-[2-(4-hydroxy-6-oxo-tetra...)
Affinity DataIC50: 890nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011030(CHEMBL123811 | 1-[2-(4-Hydroxy-6-oxo-tetrahydro-py...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed