Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50031185
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50154365BDBM50154365(2-(2-Dimethylaminomethyl-phenoxy)-5-iodo-phenylami...)
Affinity DataKi:  0.171nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110788BDBM50110788(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-methyl-...)
Affinity DataKi:  1.65nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308670BDBM50308670(N,N-Dimethyl-5-(3-fluoropropoxy)-2-(2-amino-4-meth...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308666BDBM50308666(4-Fluoro-N,N-dimethyl-2-(2-amino-4-methylphenoxy)-...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218672BDBM50218672(2-(2-((dimethylamino)methyl)-4-fluorophenoxy)-5-me...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308671BDBM50308671(N,N-Dimethyl-5-(4-fluorobutoxy)-2-(2-amino-4-methy...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308665BDBM50308665(4-Fluoro-N,N-dimethyl-2-(2-amino-4-methylphenylthi...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308668BDBM50308668(N,N-Dimethyl-5-(2-fluoroethoxy)-2-(2-amino-4-methy...)
Affinity DataKi:  401nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308671BDBM50308671(N,N-Dimethyl-5-(4-fluorobutoxy)-2-(2-amino-4-methy...)
Affinity DataKi:  406nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308669BDBM50308669(N,N-Dimethyl-4-(3-fluoropropoxy)-2-(2-amino-4-meth...)
Affinity DataKi:  445nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308669BDBM50308669(N,N-Dimethyl-4-(3-fluoropropoxy)-2-(2-amino-4-meth...)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218672BDBM50218672(2-(2-((dimethylamino)methyl)-4-fluorophenoxy)-5-me...)
Affinity DataKi:  503nMAssay Description:Displacement of [3H]WIN-35428 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308666BDBM50308666(4-Fluoro-N,N-dimethyl-2-(2-amino-4-methylphenoxy)-...)
Affinity DataKi:  503nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308667BDBM50308667(N,N-Dimethyl-4-(2-fluoroethoxy)-2-(2-amino-4-methy...)
Affinity DataKi:  519nMAssay Description:Displacement of [3H]citalopram from human cloned SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308670BDBM50308670(N,N-Dimethyl-5-(3-fluoropropoxy)-2-(2-amino-4-meth...)
Affinity DataKi:  632nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308668BDBM50308668(N,N-Dimethyl-5-(2-fluoroethoxy)-2-(2-amino-4-methy...)
Affinity DataKi:  667nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308667BDBM50308667(N,N-Dimethyl-4-(2-fluoroethoxy)-2-(2-amino-4-methy...)
Affinity DataKi:  726nMAssay Description:Displacement of [3H]WIN-35428 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308666BDBM50308666(4-Fluoro-N,N-dimethyl-2-(2-amino-4-methylphenoxy)-...)
Affinity DataKi:  960nMAssay Description:Displacement of [3H]WIN-35428 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308669BDBM50308669(N,N-Dimethyl-4-(3-fluoropropoxy)-2-(2-amino-4-meth...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]WIN-35428 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308665BDBM50308665(4-Fluoro-N,N-dimethyl-2-(2-amino-4-methylphenylthi...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308665BDBM50308665(4-Fluoro-N,N-dimethyl-2-(2-amino-4-methylphenylthi...)
Affinity DataKi:  1.22E+3nMAssay Description:Displacement of [3H]WIN-35428 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218672BDBM50218672(2-(2-((dimethylamino)methyl)-4-fluorophenoxy)-5-me...)
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308671BDBM50308671(N,N-Dimethyl-5-(4-fluorobutoxy)-2-(2-amino-4-methy...)
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of [3H]WIN-35428 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308668BDBM50308668(N,N-Dimethyl-5-(2-fluoroethoxy)-2-(2-amino-4-methy...)
Affinity DataKi:  4.19E+3nMAssay Description:Displacement of [3H]WIN-35428 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308670BDBM50308670(N,N-Dimethyl-5-(3-fluoropropoxy)-2-(2-amino-4-meth...)
Affinity DataKi:  6.98E+3nMAssay Description:Displacement of [3H]WIN-35428 from human cloned DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Tours

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308667BDBM50308667(N,N-Dimethyl-4-(2-fluoroethoxy)-2-(2-amino-4-methy...)
Affinity DataKi:  8.85E+3nMAssay Description:Displacement of [3H]nisoxetine from human cloned NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed