Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50031051
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306055BDBM50306055((S)-4-(3-(2-(1-butyl-3-(cyclohexylmethyl)-2,5-diox...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190516BDBM50190516(1-butyl-3-cyclohexylmethyl-9-(4-phenoxy-benzyl)-1,...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306053BDBM50306053((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(4-hydroxyph...)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190513BDBM50190513(9-(1,4-benzodioxane-6-yl)-1-butyl-3-cyclohexyl-1,4...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306051BDBM50306051((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(p-tolyloxy)...)
Affinity DataIC50: 79nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306050BDBM50306050((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(phenylsulfo...)
Affinity DataIC50: 86nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306054BDBM50306054((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(4-fluorophe...)
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190520BDBM50190520(rac-1-Butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-t...)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190525BDBM50190525(rac-1-Butyl-3-(cyclohexylmethyl)-9-(4-methoxybenzy...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306052BDBM50306052((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(4-methoxyph...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306049BDBM50306049((S)-3-benzyl-1-butyl-9-(3-(phenylthio)phenethyl)-1...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190523BDBM50190523(9-(1,4-benzodioxane-6-yl)-1-butyl-3-(2-methylpropy...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190522BDBM50190522((RS)-9-benzyl-1-butyl-3-isobutyl-1,4,9-triazaspiro...)
Affinity DataIC50: 900nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306048BDBM50306048((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-phenoxyphene...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP-1-alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed