Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50031051
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50306055((S)-4-(3-(2-(1-butyl-3-(cyclohexylmethyl)-2,5-diox...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190516((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenz...)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50306053((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(4-hydroxyph...)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50306051((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(p-tolyloxy)...)
Affinity DataIC50:  79nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50306050((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(phenylsulfo...)
Affinity DataIC50:  86nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50306054((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(4-fluorophe...)
Affinity DataIC50:  92nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190520((RS)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)
Affinity DataIC50:  94nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190525((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-methoxybenz...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50306052((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(4-methoxyph...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50306049((S)-3-benzyl-1-butyl-9-(3-(phenylthio)phenethyl)-1...)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190523(1-butyl-9-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)me...)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50190522((RS)-9-benzyl-1-butyl-3-isobutyl-1,4,9-triazaspiro...)
Affinity DataIC50:  900nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50306048((S)-1-butyl-3-(cyclohexylmethyl)-9-(3-phenoxyphene...)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at human CCR5 receptor overexpressed in CHO cells assessed as inhibition of MIP1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed