Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 349
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 842BDBM842(CHEMBL419923 | tert-butyl N-[(2S,3S,5R)-5-benzyl-5...)
Affinity DataIC50: 0.100nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1030BDBM1030(tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(1...)
Affinity DataIC50: 0.300nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 841BDBM841(tert-butyl N-[(2S,3S,5R)-5-benzyl-5-{[(1R,2R)-2-ca...)
Affinity DataIC50: 1.80nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 843BDBM843(tert-butyl N-[(2S,3S,5R)-5-{[(1S,2R,3R)-3-amino-2-...)
Affinity DataIC50: 1.90nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 836BDBM836(tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-1-phen...)
Affinity DataIC50: 16nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 833BDBM833(tert-butyl N-[(2S,3S,5R)-5-benzyl-5-(2,3-dihydro-1...)
Affinity DataIC50: 19nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 835BDBM835(tert-butyl N-[(2S,3S,5R)-5-benzyl-5-[(1S)-2,3-dihy...)
Affinity DataIC50: 21nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 837BDBM837(tert-butyl N-[(2S,3S,5R)-5-benzyl-5-{bicyclo[4.2.0...)
Affinity DataIC50: 22nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 758BDBM758(CHEMBL277034 | tert-butyl N-[(2S,3S,5R)-5-benzyl-5...)
Affinity DataIC50: 111nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 833BDBM833(tert-butyl N-[(2S,3S,5R)-5-benzyl-5-(2,3-dihydro-1...)
Affinity DataIC50: 130nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 840BDBM840(tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(1...)
Affinity DataIC50: 229nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 838BDBM838(tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(1...)
Affinity DataIC50: 259nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

LigandChemical structure of BindingDB Monomer ID 832BDBM832(tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-1-phen...)
Affinity DataIC50: 2.80E+3nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2004
Entry Details Article
PubMed