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Report error Found 80 Enz. Inhib. hit(s) with all data for entry = 50035943
TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011704(CHEMBL170504 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011704(CHEMBL170504 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.30nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011702(CHEMBL169870 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.5nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011713(CHEMBL430933 | {1-[1-(1-Cyclohexylmethyl-2,3-dihyd...)
Affinity DataIC50:  1.5nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011708(CHEMBL171319 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.5nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011706(CHEMBL353944 | {1-[1-[2-(1-Butyl-5,5-dimethyl-2-ox...)
Affinity DataIC50:  1.90nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011706(CHEMBL353944 | {1-[1-[2-(1-Butyl-5,5-dimethyl-2-ox...)
Affinity DataIC50:  2.40nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011702(CHEMBL169870 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  2.5nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011710(CHEMBL355458 | {1-[1-[1-Cyclohexylmethyl-2-(5-ethy...)
Affinity DataIC50:  3.30nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011710(CHEMBL355458 | {1-[1-[1-Cyclohexylmethyl-2-(5-ethy...)
Affinity DataIC50:  5.30nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011703(CHEMBL355128 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  5.5nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011693(CHEMBL352839 | {1-[1-{1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  7.70nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011698(CHEMBL354505 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  8nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011698(CHEMBL354505 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  8.5nMpH: 7.4Assay Description:Inhibitory concentration against GastricsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011695(CHEMBL170287 | {1-[1-[1-Cyclohexylmethyl-2-(5-ethy...)
Affinity DataIC50:  8.5nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011703(CHEMBL355128 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  9.30nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011696(CHEMBL170772 | {1-[1-[1-Cyclohexylmethyl-2-(1-cycl...)
Affinity DataIC50:  10nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011707(CHEMBL405692 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  10nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011695(CHEMBL170287 | {1-[1-[1-Cyclohexylmethyl-2-(5-ethy...)
Affinity DataIC50:  11nMpH: 7.4Assay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011712(CHEMBL171185 | {1-[1-{2-[1-(3-Benzylamino-propyl)-...)
Affinity DataIC50:  14nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011707(CHEMBL405692 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  14nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011714(CHEMBL435274 | {1-[1-{2-[1-(2-Benzyloxy-ethyl)-2-o...)
Affinity DataIC50:  24nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011699(CHEMBL171236 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  40nMpH: 7.4Assay Description:Inhibitory concentration against PepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011697(CHEMBL355726 | {1-[1-(1-Cyclohexylmethyl-3-dimethy...)
Affinity DataIC50:  45nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011715(CHEMBL434110 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  47nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011699(CHEMBL171236 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  71nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011706(CHEMBL353944 | {1-[1-[2-(1-Butyl-5,5-dimethyl-2-ox...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011694(CHEMBL354360 | {1-[1-[2-(5-Benzyloxymethyl-1-methy...)
Affinity DataIC50:  115nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin E(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011706(CHEMBL353944 | {1-[1-[2-(1-Butyl-5,5-dimethyl-2-ox...)
Affinity DataIC50:  115nMAssay Description:Inhibitory concentration against cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011705(CHEMBL173204 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  135nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011704(CHEMBL170504 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011700(Acetic acid 4-{2-[2-(2-tert-butoxycarbonylamino-3-...)
Affinity DataIC50:  155nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011700(Acetic acid 4-{2-[2-(2-tert-butoxycarbonylamino-3-...)
Affinity DataIC50:  157nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin E(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011702(CHEMBL169870 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  165nMAssay Description:Inhibitory concentration against cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin E(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011705(CHEMBL173204 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration against cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011698(CHEMBL354505 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  175nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011705(CHEMBL173204 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  200nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin E(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011696(CHEMBL170772 | {1-[1-[1-Cyclohexylmethyl-2-(1-cycl...)
Affinity DataIC50:  240nMAssay Description:Inhibitory concentration against cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011702(CHEMBL169870 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  250nMAssay Description:Inhibitory concentration against Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011709(CHEMBL354056 | {1-[1-(2-{1-[3-(Benzyl-benzyloxycar...)
Affinity DataIC50:  275nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011699(CHEMBL171236 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  280nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin E(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011698(CHEMBL354505 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  360nMAssay Description:Inhibitory concentration against cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50368239(CHEMBL1169539)
Affinity DataIC50:  470nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50368239(CHEMBL1169539)
Affinity DataIC50:  470nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011696(CHEMBL170772 | {1-[1-[1-Cyclohexylmethyl-2-(1-cycl...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011703(CHEMBL355128 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPepsin A(Pig)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011704(CHEMBL170504 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against PepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastricsin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011694(CHEMBL354360 | {1-[1-[2-(5-Benzyloxymethyl-1-methy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against GastricsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPepsin A(Pig)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011702(CHEMBL169870 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against PepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastricsin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011707(CHEMBL405692 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against GastricsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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