Compile Data Set for Download or QSAR
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Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 4815
TargetKetol-acid reductoisomerase (NADP(+))(Escherichia coli (strain K12))
Nankai University

LigandPNGBDBM82145(N-hydroxy-N-isopropyloxamate, IpOHA)
Affinity DataKi:  2.75E+3nM ΔG°:  -32.3kJ/molepH: 8.0 T: 30°CAssay Description:Inhibition of E. coli KARI (ketol-acid reductoisomerase) is time dependent, and activity was measured by the decrease in A340 at 30 C in solutions co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKetol-acid reductoisomerase (NADP(+))(Escherichia coli (strain K12))
Nankai University

LigandPNGBDBM82144(Cyclopropane, 5)
Affinity DataKi:  3.12E+4nM ΔG°:  -26.2kJ/molepH: 8.0 T: 30°CAssay Description:Inhibition of E. coli KARI (ketol-acid reductoisomerase) is time dependent, and activity was measured by the decrease in A340 at 30 C in solutions co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKetol-acid reductoisomerase (NADP(+))(Escherichia coli (strain K12))
Nankai University

LigandPNGBDBM82142(Cyclopropane, 3)
Affinity DataKi:  7.66E+4nM ΔG°:  -23.9kJ/molepH: 8.0 T: 30°CAssay Description:Inhibition of E. coli KARI (ketol-acid reductoisomerase) is time dependent, and activity was measured by the decrease in A340 at 30 C in solutions co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKetol-acid reductoisomerase (NADP(+))(Escherichia coli (strain K12))
Nankai University

LigandPNGBDBM82143(Cyclopropane, 4)
Affinity DataKi:  9.53E+4nM ΔG°:  -23.3kJ/molepH: 8.0 T: 30°CAssay Description:Inhibition of E. coli KARI (ketol-acid reductoisomerase) is time dependent, and activity was measured by the decrease in A340 at 30 C in solutions co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed