Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50030701
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM114543((4-butoxy-3-chloranyl-phenyl)methyl carbamimidothi...)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibition of BACE1 by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300239(3-(3-(((furan-2-ylmethyl)(methyl)amino)methyl)phen...)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibition of BACE1 by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300240(3-(3-chlorophenethyl)pyridin-2-amine | 3-[2-(3-chl...)
Affinity DataKd:  3.20E+4nMAssay Description:Binding affinity to BACE1 by fragment-based NMR screening assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50300238(2-ethylhex-2-enyl carbamimidothioate | CHEMBL57523...)
Affinity DataKd:  5.50E+5nMAssay Description:Binding affinity to BACE1 by fragment-based NMR screening assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM114543((4-butoxy-3-chloranyl-phenyl)methyl carbamimidothi...)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to BACE1 by fragment-based NMR screening assayMore data for this Ligand-Target Pair