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Report error Found 98 Enz. Inhib. hit(s) with all data for entry = 50030911
TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303863(4-Amino-5-fluoro-1-cyclopropylmethyl-2-[5-(2-phosp...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303879(4-Amino-5-fluoro-7-[3-(N,N-dimethylamino)propyl]-1...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303854(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303871(4-Amino-7-cyclopropyl-5-fluoro-1-isobutyl-2-[5-(2-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303880(4-Amino-5-fluoro-7-(4-chlorobutyl)-1-isobutyl-2-[5...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303878(4-Amino-7-(3-hydroxypropyl)-5-fluoro-1-isobutyl-2-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303872(4-Amino-7-phenyl-5-fluoro-1-isobutyl-2-[5-(2-phosp...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303874(4-Amino-7-(p-chlorophenyl)-5-fluoro-1-isobutyl-2-[...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303877(4-Amino-7-(4-methylpentyl)-5-fluoro-1-isobutyl-2-[...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303875(4-Amino-5-fluoro-7-(n-propyl)-1-isobutyl-2-[5-(2-p...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303866(4-Amino-5-fluoro-7-chloro-1-isobutyl-2-[5-(2-phosp...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303860(4-Amino-5-fluoro-1-isobutyl-2-[5-(2-phosphono)fura...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303867(4-Amino-5-fluoro-7-bromo-1-isobutyl-2-[5-(2-phosph...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303861(4-Amino-5-fluoro-1-(2-ethylbutyl)-2-[5-(2-phosphon...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303873(4-Amino-7-(p-fluorophenyl)-5-fluoro-1-isobutyl-2-[...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303856(4-Amino-5-chloro-1-isobutyl-2-[2-(5-phosphono)fura...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303876(4-Amino-7-(3,3-dimethyl-n-butyl)-5-fluoro-1-isobut...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303868(4-Amino-5-fluoro-6-chloro-1-isobutyl-2-[5-(2-phosp...)
Affinity DataIC50:  225nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303870(4-Amino-7-vinyl-5-fluoro-1-isobutyl-2-[5-(2-phosph...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303871(4-Amino-7-cyclopropyl-5-fluoro-1-isobutyl-2-[5-(2-...)
Affinity DataIC50:  350nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303859(4-Amino-7-bromo-1-isobutyl-2-[2-(5-phosphono)furan...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303879(4-Amino-5-fluoro-7-[3-(N,N-dimethylamino)propyl]-1...)
Affinity DataIC50:  400nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303858(4-Amino-5-bromo-1-isobutyl-2-[2-(5-phosphono)furan...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303878(4-Amino-7-(3-hydroxypropyl)-5-fluoro-1-isobutyl-2-...)
Affinity DataIC50:  450nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303865(4-Amino-5,7-dichloro-1-isobutyl-2-[5-(2-phosphono)...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303880(4-Amino-5-fluoro-7-(4-chlorobutyl)-1-isobutyl-2-[5...)
Affinity DataIC50:  500nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303855(5-(4-amino-5-hydroxy-1-isobutyl-1H-benzo[d]imidazo...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303854(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
Affinity DataIC50:  550nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303875(4-Amino-5-fluoro-7-(n-propyl)-1-isobutyl-2-[5-(2-p...)
Affinity DataIC50:  650nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303892(4-Amino-5-methoxy-1-isobutyl-2-[5-(2-phosphono)fur...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277565(5-(6-amino-9-neopentyl-9H-purin-8-yl)furan-2-ylpho...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303886(4-Amino-1-cyclobutylmethyl-2-[2-(5-phosphono)furan...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303885(4-Amino-1-cyclopropylmethyl-2-[2-(5-phosphono)fura...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303862(4-Amino-5-fluoro-1-(3-pentyl)-2-[5-(2-phosphono)fu...)
Affinity DataIC50:  850nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303861(4-Amino-5-fluoro-1-(2-ethylbutyl)-2-[5-(2-phosphon...)
Affinity DataIC50:  850nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303857(4-Amino-7-chloro-1-isobutyl-2-[2-(5-phosphono)fura...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303872(4-Amino-7-phenyl-5-fluoro-1-isobutyl-2-[5-(2-phosp...)
Affinity DataIC50:  900nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303870(4-Amino-7-vinyl-5-fluoro-1-isobutyl-2-[5-(2-phosph...)
Affinity DataIC50:  900nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303893(4-Amino-1-norbornylmethyl-2-[2-(5-phosphono)furany...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303864(4-Amino-5,7-dibromo-1-isobutyl-2-[2-(5-phosphono)f...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303883(4-Amino-L-propyl-2-[2-(5-phosphono)furanyl]benzimi...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303873(4-Amino-7-(p-fluorophenyl)-5-fluoro-1-isobutyl-2-[...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277564(5-(6-amino-9-isobutyl-9H-purin-8-yl)furan-2-ylphos...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303887(4-Amino-1-cyclopentylmethyl-2-[2-(5-phosphono)fura...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303884(4-Amino-l-isobutyl-2-[2-(5-phosphono)furanyl]benzi...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303876(4-Amino-7-(3,3-dimethyl-n-butyl)-5-fluoro-1-isobut...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303899(4-Amino-1-(3-hydroxybenzyl)-2-[2-(5-phosphono)fura...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303892(4-Amino-5-methoxy-1-isobutyl-2-[5-(2-phosphono)fur...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303856(4-Amino-5-chloro-1-isobutyl-2-[2-(5-phosphono)fura...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rat liver FBPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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