Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50022589
LigandPNGBDBM50306633(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human full-length Flag-tagged mTOR expressed in HEK293 cells using His6-S6K as substrate measured after 2 hrs in presence of ATP by DEL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50306633(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged p110alpha/full length untagged human p85alpha expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50306633(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human SMG1 using glutathione S-transferase-p53 as substrate by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50306633(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate measured after 15 to 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50306633(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate measured after 15 to 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50306633(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p110beta/p85alpha (unknown origin) using PIP2 as substrate measured after 15 to 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50306633(1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ATR (unknown origin) using glutathione S-transferase-p53 as substrate by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed