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Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50031079
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306587(6-Fluoro-N-(6-(4-methoxytetrahydro-2H-pyran-4-yl)p...)
Affinity DataKi:  0.430nMAssay Description:Binding affinity to 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306591(6-Fluoro-N-(6-(4-methoxytetrahydro-2H-pyran-4-yl)p...)
Affinity DataKi:  0.960nMAssay Description:Binding affinity to 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306588(6-fluoro-8-(4-methylpiperazin-1-yl)-4-oxo-N-(4-(4-...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306590(5-Methyl-4-oxo-8-(1H-pyrazol-4-yl)-1,4-dihydroquin...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity to 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306589((R)-6-methoxy-8-(4-methylpiperazin-1-yl)-N-(4-morp...)
Affinity DataKi:  12nMAssay Description:Binding affinity to 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306589((R)-6-methoxy-8-(4-methylpiperazin-1-yl)-N-(4-morp...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50306587(6-Fluoro-N-(6-(4-methoxytetrahydro-2H-pyran-4-yl)p...)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed