Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50031088
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306714(CHEMBL601873 | Isopropyl 1,1-Dimethyl-3-[4-(3-morp...)
Affinity DataIC50:  5.74E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306735(1-methylethyl 8-fluoro-1,1-dimethyl-3-{[4-(3-morph...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306744(CHEMBL601221 | Isopropyl 8-Fluoro-1,1-dimethyl-3-[...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306717(CHEMBL600415 | Isopropyl 1,1-Dimethyl-3-[4-(2-pyrr...)
Affinity DataEC50:  698nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306718(CHEMBL602894 | Isopropyl 1,1-Dimethyl-3-[4-(2-morp...)
Affinity DataEC50:  249nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306719(CHEMBL602895 | Isopropyl 1,1-Dimethyl-3-{4-[2-(4-m...)
Affinity DataEC50:  287nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306720(CHEMBL603099 | Isopropyl 3-{4-[3-(Dimethylamino)pr...)
Affinity DataEC50:  271nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306721(CHEMBL602494 | Isopropyl 1,1-Dimethyl-3-[4-(3-pyrr...)
Affinity DataEC50:  362nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306722(CHEMBL602495 | Isopropyl 1,1-Dimethyl-3-[4-(3-pipe...)
Affinity DataEC50:  424nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306723(CHEMBL592647 | Isopropyl 1,1-Dimethyl-3-{4-[3-(4-m...)
Affinity DataEC50:  194nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306724(CHEMBL602693 | Isopropyl 3-{3-[2-(Dimethylamino)et...)
Affinity DataEC50:  1.39E+3nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306725(CHEMBL602287 | Isopropyl 1,1-Dimethyl-3-[3-(2-pyrr...)
Affinity DataEC50:  1.32E+3nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306726(CHEMBL602288 | Isopropyl 1,1-Dimethyl-3-[3-(2-pipe...)
Affinity DataEC50:  894nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306727(CHEMBL605996 | Isopropyl 1,1-Dimethyl-3-[3-(2-morp...)
Affinity DataEC50:  855nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306728(CHEMBL601251 | Isopropyl 1,1-Dimethyl-3-{3-[2-(4-m...)
Affinity DataEC50:  2.87E+3nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306729(CHEMBL601459 | Isopropyl 3-{3-[3-(Dimethylamino)pr...)
Affinity DataEC50:  617nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306730(CHEMBL602059 | Isopropyl 1,1-Dimethyl-3-[3-(3-pyrr...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306731(CHEMBL604335 | Isopropyl 1,1-Dimethyl-3-[3-(3-pipe...)
Affinity DataEC50:  1.12E+3nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306732(CHEMBL602061 | Isopropyl 1,1-Dimethyl-3-[3-(3-morp...)
Affinity DataEC50:  796nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306733(CHEMBL602709 | Isopropyl 1,1-Dimethyl-3-{3-[3-(4-m...)
Affinity DataEC50:  1.02E+3nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28542(WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...)
Affinity DataEC50:  152nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306734(CHEMBL603278 | isopropyl 3-(3,4-difluorobenzoyl)-9...)
Affinity DataEC50:  112nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306735(1-methylethyl 8-fluoro-1,1-dimethyl-3-{[4-(3-morph...)
Affinity DataEC50:  88nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28542(WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306734(CHEMBL603278 | isopropyl 3-(3,4-difluorobenzoyl)-9...)
Affinity DataEC50:  45nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306736(CHEMBL604334 | Isopropyl 1,1-Dimethyl-3-[3-(morpho...)
Affinity DataEC50:  1.58E+3nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306737(CHEMBL601434 | Isopropyl 1,1-Dimethyl-3-{3-[(4-met...)
Affinity DataEC50:  368nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306738(CHEMBL601647 | Isopropyl 1,1-Dimethyl-3-[3-(piperi...)
Affinity DataEC50:  534nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306739(CHEMBL602883 | Isopropyl 1,1-Dimethyl-3-[3-(pyrrol...)
Affinity DataEC50:  340nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306740(CHEMBL603086 | Isopropyl 1,1-Dimethyl-3-[4-(morpho...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306741(CHEMBL603282 | Isopropyl 8-Fluoro-1,1-dimethyl-3-[...)
Affinity DataEC50:  447nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306742(CHEMBL602681 | Isopropyl 1,1-Dimethyl-3-[4-(2-morp...)
Affinity DataEC50:  602nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306743(CHEMBL611221 | Isopropyl 8-Fluoro-1,1-dimethyl-3-[...)
Affinity DataEC50:  342nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306735(1-methylethyl 8-fluoro-1,1-dimethyl-3-{[4-(3-morph...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306744(CHEMBL601221 | Isopropyl 8-Fluoro-1,1-dimethyl-3-[...)
Affinity DataEC50:  99nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306744(CHEMBL601221 | Isopropyl 8-Fluoro-1,1-dimethyl-3-[...)
Affinity DataEC50:  188nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306714(CHEMBL601873 | Isopropyl 1,1-Dimethyl-3-[4-(3-morp...)
Affinity DataEC50:  108nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306716(CHEMBL604761 | Isopropyl 3-{4-[2-(Dimethylamino)et...)
Affinity DataEC50:  439nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306718(CHEMBL602894 | Isopropyl 1,1-Dimethyl-3-[4-(2-morp...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306714(CHEMBL601873 | Isopropyl 1,1-Dimethyl-3-[4-(3-morp...)
Affinity DataEC50:  101nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306715(CHEMBL603492 | Isopropyl 1,1-Dimethyl-3-[4-(2-pipe...)
Affinity DataEC50:  1.07E+3nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed