Compile Data Set for Download or QSAR
Report error Found 170 Enz. Inhib. hit(s) with all data for entry = 50031107
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307150BDBM50307150(2,4-Diamino-5-methyl-6-(2',6'-dimethylphenylthio)p...)
Affinity DataIC50: 5.11nMAssay Description:Inhibition of Toxoplasma gondii DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307151BDBM50307151(5-methyl-6-(5,6,7,8-tetrahydronaphthalen-1-ylthio)...)
Affinity DataIC50: 160nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18267BDBM18267(CHEMBL331986 | 6-[(2,5-dimethoxyphenyl)sulfanyl]-5...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307152BDBM50307152(2,4-Diamino-5-methyl-6-(2',4',5'-trichlorophenylth...)
Affinity DataIC50: 212nMAssay Description:Inhibition of Toxoplasma gondii DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307150BDBM50307150(2,4-Diamino-5-methyl-6-(2',6'-dimethylphenylthio)p...)
Affinity DataIC50: 388nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059941BDBM50059941(8-benzyl-9H-purine-2,6-diamine | CHEMBL102303)
Affinity DataIC50: 500nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307153BDBM50307153(2,4-Diamino-5-methyl-6-(3',5'-dimethylphenylthio)p...)
Affinity DataIC50: 572nMAssay Description:Inhibition of Toxoplasma gondii DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307182BDBM50307182(5-(3-(4-(benzyloxy)phenyl)propyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 660nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307169BDBM50307169(2,4-Diamino-5-methyl-6-(3',4',5'-trimethoxyphenylt...)
Affinity DataIC50: 686nMAssay Description:Inhibition of Toxoplasma gondii DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307155BDBM50307155(5-((5,6,7,8-tetrahydronaphthalen-1-ylthio)methyl)-...)
Affinity DataIC50: 810nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059931BDBM50059931(8-(2,4,6-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 840nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307160BDBM50307160(5-((methyl(5,6,7,8-tetrahydronaphthalen-1-yl)amino...)
Affinity DataIC50: 870nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059921BDBM50059921(8-(2,4-dimethoxyphenyl)-9H-purine-2,6-diamine | 8-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059924BDBM50059924(4-(2,6-diamino-9H-purin-8-yl)-2,6-dimethoxyphenol ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057313BDBM50057313(5-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-7H...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307183BDBM50307183(5-(3-(5,6,7,8-tetrahydronaphthalen-2-yl)propyl)-7H...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149470BDBM50149470(6-(2-Methoxy-phenylsulfanyl)-5-methyl-7H-pyrrolo[2...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307159BDBM50307159(5-(3-(3,4,5-trimethoxyphenyl)propyl)-7H-pyrrolo[2,...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307183BDBM50307183(5-(3-(5,6,7,8-tetrahydronaphthalen-2-yl)propyl)-7H...)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127154BDBM50127154(5-[(5,6,7,8-Tetrahydro-naphthalen-1-ylamino)-methy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307158BDBM50307158(5-(3-(2,5-dichlorophenyl)propyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307184BDBM50307184(5-(3-(5,6,7,8-tetrahydronaphthalen-1-yl)propyl)-7H...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035273BDBM50035273(5-[(3,4-Dichloro-phenylamino)-methyl]-7H-pyrrolo[2...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307184BDBM50307184(5-(3-(5,6,7,8-tetrahydronaphthalen-1-yl)propyl)-7H...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059923BDBM50059923(8-(2,4,5-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18262BDBM18262(5-methyl-6-(naphthalen-2-ylsulfanyl)-7H-pyrrolo[2,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059941BDBM50059941(8-benzyl-9H-purine-2,6-diamine | CHEMBL102303)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307182BDBM50307182(5-(3-(4-(benzyloxy)phenyl)propyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059939BDBM50059939(8-(2,5-Dimethoxy-phenyl)-9H-purine-2,6-diamine | 8...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035271BDBM50035271(5-[(2,5-Dimethoxy-phenylamino)-methyl]-7H-pyrrolo[...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059922BDBM50059922(8-(2,3,4-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059931BDBM50059931(8-(2,4,6-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149471BDBM50149471(6-(3-methoxyphenylthio)-5-methyl-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059933BDBM50059933(8-(3,4,5-Trimethoxy-phenyl)-9H-purine-2,6-diamine ...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149470BDBM50149470(6-(2-Methoxy-phenylsulfanyl)-5-methyl-7H-pyrrolo[2...)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059921BDBM50059921(8-(2,4-dimethoxyphenyl)-9H-purine-2,6-diamine | 8-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057311BDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18266BDBM18266(6-[(4-methoxyphenyl)sulfanyl]-5-methyl-7H-pyrrolo[...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307154BDBM50307154(5-(3-phenylpropyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307152BDBM50307152(2,4-Diamino-5-methyl-6-(2',4',5'-trichlorophenylth...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307155BDBM50307155(5-((5,6,7,8-tetrahydronaphthalen-1-ylthio)methyl)-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057313BDBM50057313(5-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-7H...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059940BDBM50059940(8-(3,5-Dimethoxy-phenyl)-9H-purine-2,6-diamine | 8...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057316BDBM50057316(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059939BDBM50059939(8-(2,5-Dimethoxy-phenyl)-9H-purine-2,6-diamine | 8...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059922BDBM50059922(8-(2,3,4-trimethoxyphenyl)-9H-purine-2,6-diamine |...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035268BDBM50035268(5-Phenylaminomethyl-7H-pyrrolo[2,3-d]pyrimidine-2,...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041177BDBM50041177(5-((3,4,5-trichlorophenylamino)methyl)furo[2,3-d]p...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307156BDBM50307156(5-(3-(2,5-dimethoxyphenyl)propyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 4.05E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035272BDBM50035272(5-[(3,4-Dimethoxy-phenylamino)-methyl]-7H-pyrrolo[...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
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